Clinical Study on Maxing Shigan Tang Combined with Oxygen Atomization Therapy with Budesonide Suspension for Inhalation in the Treatment of Pediatric Pneumonia
Abstract: Objective: To observe the clinical effect of Maxing Shigan tang combined with oxygen atomization therapy with budesonide suspension for inhalation in the treatment of pediatric pneumonia. Methods:A total of 98 cases of children with pediatric pneumonia were randomly divided into the control group and the study group, with 49 cases in each group. The control group was treated with oxygen atomization therapy with budesonide suspension for inhalation, and the study group was treated with Maxing Shigan tang combined with oxygen atomization therapy with budesonide suspension for inhalation. Both groups were treated for two weeks. The clinical effects,the improvement of cough and fever,the lung function[forced vital capacity(FVC), 50% forced expiratory flow(FEF50% ), peak expiratory flow(PEF) and the percentage of forced expiratory vdume in one second to the predicted value(FEV1% )], and the changes in scores of symptoms and signs before and after treatment in the two groups were compared. Results:After treatment for one and two weeks,the total effective rate was 95.9% and 100%in the study group,and 59.2%and 87.8% in the control group,and there being significant difference being found in the comparison of the total effective rate at the same time period between the two groups(P<0.05). There were 47 cases(95.9%) of complete disappearance of cough in the study group and 29 cases(59.2%) in the control group, the difference being significant(P<0.05). Before treatment, there was no significant difference being found in the comparison of scores of symptoms and signs between the two groups(P> 0.05). After treatment for one and two weeks,the scores of symptoms and signs in the two groups were significantly decreased when compared with those before treatment(P<0.05),and the scores at the same period in the study group were lower than those in the control group(P<0.05). The average disappearance time of cough and average antipyretic time in the study group were shorter than those in the control group, differences being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of FVC%,FEF50%,PEF and FEV1% between the two groups(P>0.05). After two-week treatment, the levels of FVC% , FEF50% , PEF and FEV1% in the two groups were increased when compared with those before treatment(P<0.05),and the levels of FVC%,FEF50%,PEF and FEV1% in the study group were higher than those in the control group(P<0.05). Conclusion: The application of Maxing Shigan tang combined with oxygen atomization therapy with budesonide suspension for inhalation in the treatment of pediatric pneumonia can enhance total clinical effective rate and significantly improve symptoms, signs and lung function, whose curative effect was better than that of simple western medicine.