滑膜炎片联合美洛昔康片治疗膝关节滑膜炎临床研究
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R686.7

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Clinical Study on Huamoyan Pills Combined with Meloxicam Tablets for Gonarthromeningitis
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    摘要:

    目的:观察滑膜炎片联合美洛昔康片治疗膝关节滑膜炎的临床效果。方法:将90 例膝关节滑膜炎患者随机分为常规组与治疗组各45 例。常规组口服美洛昔片并行膝关节康复训练,治疗组在常规组基础上联用滑膜炎片治疗。比较2 组治疗前后外周血中炎性因子水平,比较2 组临床疗效、滑膜炎恢复情况及治疗期间不良反应发生情况。结果:治疗组治疗总有效率93.33%,高于常规组77.78% (P<0.05)。与同组治疗前比较,治疗后2 组肿瘤坏死因子-α (TNF-α)、白细胞介素-1β (IL-1β)、红细胞沉降率(ESR) 水平及积液、滑膜增生、滑膜血流信号评分均降低(P<0.05);与常规组治疗后比较,治疗组治疗后TNF-α、IL-1β、ESR水平及积液、滑膜增生、滑膜血流信号评分均较低(P<0.05)。治疗期间2 组均未发生不良反应。结论:滑膜炎片联合美洛昔康片治疗膝关节滑膜炎可有效改善患者症状,减轻炎性反应,且安全性高。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Huamoyan pills combined with meloxicam tablets for gonarthromeningitis. Methods:A total of 90 cases of patients with gonarthromeningitis were randomly divided into the routine group and the treatment group,with 45 cases in each group. The routine group was given the oral administration of meloxicam tablets and the knee joint rehabilitation,and the treatment group was additionally treated with Huamoyan pills based on the treatment of the routine group. The levels of inflammatory factors in peripheral blood before and after treatment were compared between the two groups. The clinical effects, the synovitis recovery and the adverse reactions during treatment were compared between the two groups. Results:The total effective rate was 93.33% in the treatment group, higher than that of 77.78% in the routine group(P<0.05). After treatment,levels of tumor necrosis factor-α (TNF- α),interleukin- 1β(IL- 1β) and erythrocyte sedimentation rate(ESR),as well as scores of hydrops, synovial hyperplasia and synovial blood flow signal in the two groups were decreased when compared with those before treatment(P<0.05),and the above three levels and three scores in the treatment group were lower than those in the routine group(P<0.05). There was no adverse reaction in the two groups during treatment. Conclusion: Huamoyan pills combined with meloxicam tablets for gonarthromeningitis can effectively improve symptoms,and relieve inflammatory responses,with high safety.

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何冰冰,王福音,干贤亮.滑膜炎片联合美洛昔康片治疗膝关节滑膜炎临床研究[J].新中医,2022,54(17):135-137

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  • 在线发布日期: 2022-09-06
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