龙胆泻肝汤联合西药治疗带状疱疹临床研究
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R752.12

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Clinical Study on Longdan Xiegan Tang Combined with Western Medicine for Herpes Zoster
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    摘要:

    目的:观察龙胆泻肝汤联合西药治疗带状疱疹的临床疗效。方法:选取120 例带状疱疹患者,按随机数字表法分为治疗组、对照组各60 例,对照组采用西药治疗,治疗组在对照组基础上联合龙胆泻肝汤口服治疗。比较2 组临床疗效及不良反应发生情况,比较2 组止疱时间、止痛时间、结痂时间的差异,比较2 组治疗后2 个月后遗神经痛发生率。结果:治疗后,治疗组临床疗效总有效率为90.0%,对照组为75.0%,2 组比较,差异有统计学意义(P<0.05)。治疗组止疱时间、止痛时间、结痂时间均短于对照组,差异均有统计学意义(P<0.05)。随访发现,治疗组后遗神经痛发生率为1.7%,对照组为13.3%,2 组比较,差异有统计学意义(P<0.05)。治疗期间,治疗组出现恶心1 例,腹泻1 例,对照组胃部不适1 例,恶心1 例,2 组不良反应比较,差异无统计学意义(P>0.05)。结论:龙胆泻肝汤联合西药治疗带状疱疹疗效显著,可缩短带状疱疹的病程,降低带状疱疹后遗神经痛的发生率,用药安全性较高。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Longdan Xiegan tang combined with western medicine on herpes zoster. Methods:A total of 120 patients with herpes zoster were divided into the treatment group and the control group according to the random number table method , with 60 cases in each group. The control group was treated with western medicine,and the treatment group was additionally treated with Longdan Xiegan tang orally based on the treatment of the control group. The clinical effects and adverse reactions were compared between the two groups. The time of controlling herpes, analgesia and incrustation and incidence of postherpetic neuralgia two months after treatment were compared between the two groups. Results:After treatment,the total effective rate was 90.0% in the treatment group and 75.0% in the control group,the difference being significant(P<0.05). The time of controlling herpes, analgesia and incrustation in the treatment group was shorter than that in the control group, differences being significant(P<0.05). During follow- up, the incidence of postherpetic neuralgia was 1.7% in the treatment group and 13.3% in the control group,the difference being significant(P<0.05). During treatment,one case of nausea and one case of diarrhea were found in the treatment group,and one case of nausea was found in the control group,there being no significance in the difference(P>0.05). Conclusion: The therapy of Longdan Xiegan tang combined with western medicine has a significant curative effect on herpes zoster,shorten the course of disease,and reduce the incidence of postherpetic neuralgia,with high administration safety.

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曹益红.龙胆泻肝汤联合西药治疗带状疱疹临床研究[J].新中医,2022,54(17):47-50

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  • 在线发布日期: 2022-09-06
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