Abstract： Objective： To systematically evaluate the clinical effect of Chinese medicine external treatment on children with constipation，and to provide evidence-based basis for its rational use in clinical practice. Methods：Literatures involved randomized controlled trials on the application of Chinese medicine external treatment in children constipation were searched from The Cochrane Library， PubMed， EMBASE， Wanfang Database， China Biomedical Database， CNQI database and VIP database from the date when the databases were established to March 2021. Literatures were retrieved， screened and evaluated independently by two researchers，and meta-analysis was performed via RevMan5.3 software. Results：A total of 12 literatures were included，and a total of 1 528 children were included. The combined results of meta- analysis showed that the therapeutic effect between the two groups was statistically significant(P＜0.05). There was significant difference in the comparison of the score of stool trait between the two groups(P＜0.05). There was significant difference in the comparison of the symptom score of defecation difficulty between the two groups(P＜0.05). There was significant difference in the comparison of symptom scores of abdominal pain and abdominal distension between the two groups(P＜0.05). There was significant difference in the comparison of Chinese medicine syndrome scores between the two groups (P＜0.05). The funnel plot of the therapeutic effect on children with constipation showed that there was no bias in the literatures of this study. Conclusion：The clinical effect of Chinese medicine external treatment on children with constipation is better than that of the control group， and the improvement of the main clinical symptoms in the experiment group is better than that in the control group. However，the literatures included are of low quality and limited in number， and more high- quality studies with large samples are needed to verify it in the future.