清热祛湿外洗液的薄层鉴别及稳定性研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R284.1

基金项目:

广州中医药大学第三附属医院科研创新基金项目(Sy2020008)


Thin-Layer Identification and Stability Study of Qingre Qushi Lotion
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:建立清热祛湿外洗液中苦参、黄柏、冰片的薄层鉴别方法,并考察其质量稳定性。方法:通过薄层色谱法对清热祛湿外洗液处方中的苦参、黄柏、冰片进行鉴别,采用影响因素试验、加速试验和长期试验考察清热祛湿外洗液的稳定性。结果:苦参、黄柏、冰片薄层色谱图中的斑点清晰、特征明显且阴性对照样品没有干扰。3 批产品在长期试验和加速试验中均具有较好的稳定性,制剂稳定性重点考察项目均符合标准规定。结论:清热祛湿外洗液制剂质量稳定且可控,薄层色谱法重复性好、专属性高,可作为清热祛湿外洗液的质量控制方法。

    Abstract:

    Abstract:Objective:To establish a thin-layer identification method for Radix Sophorae Flavescentis, Cortex Phellodendri Chinensis and Borneolum Syntheticum in Qingre Qushi lotion, and to investigate its quality stability. Methods:The Radix Sophorae Flavescentis,Cortex Phellodendri Chinensis and Borneolum Syntheticum in the prescription of Qingre Qushi lotion were identified by the method of thin- layer chromatography. The stability of Qingre Qushi lotion was investigated by influencing factors tests, accelerated tests and long- term tests. Results: The spots of Radix Sophorae Flavescentis, Cortex Phellodendri Chinensis and Borneolum Syntheticum in the thin- layer chromatograms were clear, with obvious characteristics and no interference from the negative control sample. Three batches of products showed good stability during long- term tests and accelerated tests, and the key inspection items of preparation stability met the standard. Conclusion:The preparation quality of Qingre Qushi lotion is stable and controllable, and the thin- layer chromatography method has good repeatability and high specificity, which can be used as the quality control method of Qingre Qudu lotion.

    参考文献
    相似文献
    引证文献
引用本文

陈土荣,周艳,吴雪茹,袁伟彬,赵毛香,范俊锋,张丽芳.清热祛湿外洗液的薄层鉴别及稳定性研究[J].新中医,2022,54(15):1-5

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2022-08-04
  • 出版日期: