Abstract： Objective： To observe the clinical effect of integrated Chinese and western medicine therapy combined with point catgut embedment on unstable angina pectoris. Methods ： A total of 120 patients with unstable angina pectoris who met the inclusion criteria were divided into the combination group(point catgut embedment combined with western medicine) and the western medicine group according to the random number table method，with 60 cases in each group. The western medicine group was treated with routine western medicine， and the combination group was treated with point catgut embedment based on the treatment of routine western medicine. The clinical effects in the two groups were evaluated after one year of treatment， and the Chinese medicine syndrome scores， the scores of Seattle Angina Questionnaire(SAQ)， and the incidence of acute myocardial infarction were compared. Results： The incidence of AMI was 5.0% in the combination group and 16.7% in the western medicine group， the difference being significant(P＜0.05). In the combination group， there were significant differences being found in the comparisons of Chinese medicine syndromes scores of precordial pain，lack of strength and shortness of breath，palpitation and spontaneous sweating，cold body and limbs，and pain in chest when cold before and after treatment(P＜0.05). After treatment，there were significant differences being found in the comparisons of each Chinese medicine syndrome score between the two groups， differences being significant(P＜0.05). After treatment，the scores of SAQ in the combination group were increased， including scores of degree of activity limitation， the stable state of angina pectoris and the attack of angina pectoris， and there were significant differences in the comparisons of them before and after treatment(P＜0.01). After treatment，the SAQ scores in the western medicine group were compared with those before treatment， differences being significant(P＜0.05). After treatment， the above three scores of SAQ were compared between the two groups，differences being significant(P＜0.05). The total effective rate of electrocardiogram was 94.7% in the combination group and 74.0% in the western medicine group， the difference being significant(P＜0.05). The total effective rate of unstable angina pectoris was 94.7% in the combination group and 74.0% in the western medicine group，the difference being significant (P＜0.05). Conclusion： Integrated Chinese and western medicine therapy combined with point catgut embedment can relieve the clinical symptoms of patients with unstable angina pectoris， reduce the incidence of myocardial infarction，and the effect is better than the standard medical treatment alone.