祛痰化浊止眩方联合替米沙坦治疗老年原发性高血压痰湿壅盛证临床研究
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R544.1

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Clinical Study on Qutan Huazhuo Zhixuan Prescription Combined with Telmisartan for Elderly Patients with Essential Hypertension with Phlegm-Dampness Excessiveness and Obstruction Syndrome
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    摘要:

    目的:观察祛痰化浊止眩方联合替米沙坦治疗老年原发性高血压(EHT)痰湿壅盛证的临床疗效。方法:选取 160 例老年 EHT 痰湿壅盛证患者,按抽签法分成对照组和观察组各 80 例。对照组给予替米沙坦片治疗,观察组在对照组基础上给予祛痰化浊止眩方治疗,2 组均治疗 8 周。比较 2 组临床疗效及治疗前后中医证候积分、血压和血液流变学指标。结果:观察组总有效率 86.25%,高于对照组 67.50%(P<0.05)。治疗后,2 组中医证候积分、收缩压(SBP)、舒张压(DBP)、血浆黏度、全血高切黏度、全血低切黏度、纤维蛋白原及红细胞聚集指数均较治疗前降低(P<0.05),观察组中医证候积分、SBP、DBP、血浆黏度、全血高切黏度、全血低切黏度、纤维蛋白原及红细胞聚集指数均低于对照组(P<0.05)。结论:祛痰化浊止眩方联合替米沙坦治疗老年 EHT 痰湿壅盛证有助于提升临床疗效,改善血液流变学指标。

    Abstract:

    Abstract: Objective: To observe the clinical effect of the therapy of Qutan Huazhuo Zhixuan prescription combined with telmisartan on senile essential hypertension(EHT) with phlegm- dampness excessiveness and obstruction syndrome. Methods: A total of 160 elderly EHT patients with phlegm- dampness excessiveness and obstruction syndrome were selected and divided into the control group and the observation group according to the lottery method,with 80 cases in each group. The control group was treated with telmisartan tablets,and the observation group was additionally treated with Qutan Huazhuo Zhixuan prescription based on the treatment of the control group. Both groups were treated for eight weeks. The Chinese medicine syndrome scores,blood pressure and indexes of hemorheology before and after treatment and clinical effects were compared between the two groups. Results:The total effective rate was 86.25% in the observation group, higher than that of 67.50% in the control group(P<0.05). After treatment,the Chinese medicine syndrome scores,systolic blood pressure(SBP),diastolic blood pressure (DBP),plasma viscosity,high-shear whole blood viscosity,low-shear whole blood viscosity,fibrinogen and red cell aggregation in the two groups were decreased when compared with those before treatment(P< 0.05),and the above indexes in the observation group were lower than those in the control group(P<0.05). Conclusion:The therapy of Qutan Huazhuo Zhixuan prescription combined with telmisartan for elderly EHT patients with phlegm-dampness excessiveness and obstruction syndrome helps to enhance the clinical effect and improve the indexes of hemorheology.

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朱来来.祛痰化浊止眩方联合替米沙坦治疗老年原发性高血压痰湿壅盛证临床研究[J].新中医,2022,54(14):71-74

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  • 在线发布日期: 2022-07-21
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