Abstract：As a common and frequently-occurring clinical disease，insomnia seriously affects physical and mental health and quality of life of patients. This paper summarizes HU Bin's academic thought and experience of diagnosis and treatment in treating insomnia from the spleen and stomach. HU emphasizes on “unblocking” and “harmony”， focusing on the source of qi and blood production and the orderly ascending and descending of qi movement. In this way， the heart spirit is nourished and hence the theoretical connotation of treating insomnia from the spleen and stomach is further deepened.