Abstract: Objective: To observe the clinical effect of Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23) for senile osteoporosis of spleen- kidney yang deficiency type. Methods:A total of 112 cases of senile patients with osteoporosis of spleen-kidney yang deficiency type were selected and divided into the control group and the observation group according to the random number table method, with 56 cases in each group. The control group was given oral administration of Caltrate D300,and the observation group was additionally treated with Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23). Both groups were treated for three months. The clinical effects in the two groups were compared. Before and after treatment, the changes in Chinese medicine syndrome scores, bone mineral density, bone alkaline phosphatase(BALP) and bone Gla protein(BGP) in serum, Berg Balance Scale(BBS) scores in the two groups were compared. Results: After treatment, the ten scores and the total scores of Chinese medicine syndromes in the two groups were decreased when compared with those before treatment, and the ten scores and the total score of Chinese medicine syndromes in the observation group were lower than those in the control group, differences being significant(P<0.05). After treatment, the total effective rate of clinical effect was 92.86% in the observation group and 76.79% in the control group, the difference being significant(P<0.05). After treatment,the bone mineral density of lumbar vertebra and femur in the two groups was increased when compared with those before treatment,and the bone mineral density of lumbar vertebra and femur in the observation group was higher than that in the control group, differences being significant(P<0.05). After treatment,the levels of calcium,phosphorus,BALP and BGP in serum in the two groups were increased when compared with those before treatment,differences being significant(P<0.05);the above four levels in the observation group were higher than those in the control group,and the levels of BALP and BGP in serum between the two groups showed significance in differences(P<0.05). After three- month treatment, the BBS scores in the two groups were increased when compared with those before treatment, and the BBS score in the observation group was higher than that in the control group, differences being significant(P<0.05). Conclusion:Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23) has a certain curative effect in treating senile osteoporosis of spleen- kidney yang deficiency type,which can effectively improve bone metabolism,bone mineral density and body balance ability and relieve clinical symptoms.