补肾活血通痹汤联合针刺肾俞穴治疗脾肾阳虚型老年骨质疏松症临床研究
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R259

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浙江省中医药科技计划(2013ZA114)


Clinical Study on Bushen Huoxue Tongbi Tang Combined with Acupuncture at Shenshu Point for Senile Osteoporosis of Spleen-Kidney Yang Deficiency Type
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    摘要:

    目的:观察补肾活血通痹汤联合针刺肾俞穴对老年骨质疏松症(脾肾阳虚证) 的临床疗效。方法:选取112 例老年骨质疏松症(脾肾阳虚证) 患者,按随机数字表法分为对照组、观察组各56 例。对照组给予钙尔奇D300 咀嚼片口服治疗,观察组给予补肾活血通痹汤联合针刺肾俞穴治疗,2 组均治疗3 个月。比较2 组临床疗效,比较2 组治疗前后中医证候评分、骨密度、血清骨碱性磷酸酶(BALP) 及钙素(BGP)、Berg 平衡量表(BBS) 评分的变化。结果:治疗后,2 组10 项中医证候评分及总分均较治疗前下降,观察组10 项中医证候评分及总分均低于对照组,差异均有统计学意义(P<0.05)。治疗后,观察组临床疗效总有效率为92.86%,对照组为76.79%,2 组比较,差异有统计学意义(P<0.05)。治疗后,2 组腰椎骨密度、股骨骨密度均较治疗前升高,观察组腰椎骨密度、股骨骨密度均高于对照组,差异均有统计学意义(P<0.05)。治疗后,2 组血钙、血磷、BALP、BGP 水平均较治疗前升高,差异均有统计学意义(P<0.05);治疗后,观察组上述4 项水平均高于对照组,其中BALP、BGP 水平与对照组比较,差异均有统计学意义(P<0.05)。治疗3 个月后,2 组BBS 评分均较治疗前升高,观察组BBS 评分高于对照组,差异均有统计学意义(P<0.05)。结论:补肾活血通痹汤联合针刺肾俞穴治疗老年骨质疏松症(脾肾阳虚证) 疗效确切,能有效改善骨代谢,提高骨密度,减轻患者临床症状,增加身体平衡能力。

    Abstract:

    Abstract: Objective: To observe the clinical effect of Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23) for senile osteoporosis of spleen- kidney yang deficiency type. Methods:A total of 112 cases of senile patients with osteoporosis of spleen-kidney yang deficiency type were selected and divided into the control group and the observation group according to the random number table method, with 56 cases in each group. The control group was given oral administration of Caltrate D300,and the observation group was additionally treated with Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23). Both groups were treated for three months. The clinical effects in the two groups were compared. Before and after treatment, the changes in Chinese medicine syndrome scores, bone mineral density, bone alkaline phosphatase(BALP) and bone Gla protein(BGP) in serum, Berg Balance Scale(BBS) scores in the two groups were compared. Results: After treatment, the ten scores and the total scores of Chinese medicine syndromes in the two groups were decreased when compared with those before treatment, and the ten scores and the total score of Chinese medicine syndromes in the observation group were lower than those in the control group, differences being significant(P<0.05). After treatment, the total effective rate of clinical effect was 92.86% in the observation group and 76.79% in the control group, the difference being significant(P<0.05). After treatment,the bone mineral density of lumbar vertebra and femur in the two groups was increased when compared with those before treatment,and the bone mineral density of lumbar vertebra and femur in the observation group was higher than that in the control group, differences being significant(P<0.05). After treatment,the levels of calcium,phosphorus,BALP and BGP in serum in the two groups were increased when compared with those before treatment,differences being significant(P<0.05);the above four levels in the observation group were higher than those in the control group,and the levels of BALP and BGP in serum between the two groups showed significance in differences(P<0.05). After three- month treatment, the BBS scores in the two groups were increased when compared with those before treatment, and the BBS score in the observation group was higher than that in the control group, differences being significant(P<0.05). Conclusion:Bushen Huoxue Tongbi tang combined with acupuncture at Shenshu point(BL23) has a certain curative effect in treating senile osteoporosis of spleen- kidney yang deficiency type,which can effectively improve bone metabolism,bone mineral density and body balance ability and relieve clinical symptoms.

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丁超儿,周志华,计少华.补肾活血通痹汤联合针刺肾俞穴治疗脾肾阳虚型老年骨质疏松症临床研究[J].新中医,2022,54(13):88-92

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  • 在线发布日期: 2022-07-07
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