Abstract: Objective: To investigate the correlation between prognosis and Chinese medicine constitution types in patients with non- small cell lung cancer(NSCLC). Methods: A total of 200 cases of NSCLC patients were selected; the factors affecting the prognosis of NSCLC patients were collected, including age, gender, pathological type, smoking index,weight loss,TNM staging,karnofsky(KPS) score and family history;the correlation between prognosis and Chinese medicine constitution types in NSCLC patients was studied by Logistic analysis. Results: Among 200 cases of patients, there were 29 cases with moderate constitution, accounting for 14.50% ; there were 20 cases with special intrinsic constitution,accounting for 10.00%;there were 22 cases with qi-depression constitution,accounting for 11.00%;there were 23 cases with dampness- heat constitution, accounting for 11.50% ; there were 20 cases with phlegm- dampness constitution, accounting for 20.00% ; there were 26 cases with blood stasis constitution, accounting for 13.00% ; there were 21 cases with yin- deficiency constitution, accounting for 10.50% ; there were 17 cases of yang- deficiency constitution, accounting for 8.50% ; there were 22 cases with qi- deficiency constitution, accounting for 11.00% . The factors including age,gender,pathological type,smoking index,KPS score and family history had no significant effect on Chinese medicine constitutions,there being no significance in the difference(P>0.05);TNM staging and weight loss had a significant effect on Chinese medicine constitutions, differences being significant(P<0.05). TNM staging was negatively correlated with moderate constitution, phlegm- dampness constitution and qi- deficiency constitution(P<0.05), and positively correlated with yin- deficiency constitution and yang- deficiency constitution(P<0.05). Weight loss was positively correlated with yin- deficiency constitution and negatively correlated with phlegm- dampness constitution(P<0.05). Conclusion:There is a certain correlation between TNM staging as well as weight loss and Chinese medicine constitutions in NSCLC patients. The higher the TNM stage is, the lower the probability of moderate constitution, phlegm- dampness constitution and qi-deficiency constitution,and the higher the probability of yin-deficiency constitution and yang-deficiency constitution. Among the patients with weight loss,there are more with yin-deficiency constitution and fewer with phlegmdampness constitution.