非小细胞肺癌患者预后与中医体质类型相关性研究
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R734.2

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Study on Correlation Between Prognosis and Chinese Medicine Constitution Types in Patients with Non-Small Cell Lung Cancer
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    摘要:

    目的:探讨非小细胞肺癌(NSCLC) 患者预后与中医体质类型的相关性。方法:选取NSCLC 患者200 例,收集影响NSCLC 预后的因素,包括年龄、性别、病理类型、吸烟指数、体质量下降、TNM 分期、卡氏(KPS) 评分、家族史,采用Logistic 分析NSCLC 患者预后与中医体质类型的相关性。结果:200 例患者中29 例平和质,占14.50%;20 例特禀质,占10.00%;22 例气郁质,占11.00%;23 例湿热质,占11.50%;20 例痰湿质,占20.00%;26 例血瘀质,占13.00%;21 例阴虚质,占10.50%;17 例阳虚质,占8.50%;22 例气虚质,占11.00%。年龄、性别、病理类型、吸烟指数、KPS 评分、家族史等因素对中医体质影响不大,差异没有统计学意义(P>0.05);TNM 分期、体质量下降情况对中医体质影响明显,差异均有统计学意义(P<0.05)。TNM 分期与平和质、痰湿质、气虚质呈负相关性(P<0.05),TNM 分期与阴虚质、阳虚质呈正相关性(P<0.05);体重下降与阴虚质呈正相关性(P<0.05),与痰湿质呈负相关性(P<0.05)。结论:NSCLC 患者TNM 分期、体质量降低与中医体质存在一定的相关性,TNM 分期越高,出现平和质、痰湿质、气虚质的概率越低,出现阴虚质、阳虚质的概率越高;体质量降低患者较多为阴虚质,而痰湿质较少。

    Abstract:

    Abstract: Objective: To investigate the correlation between prognosis and Chinese medicine constitution types in patients with non- small cell lung cancer(NSCLC). Methods: A total of 200 cases of NSCLC patients were selected; the factors affecting the prognosis of NSCLC patients were collected, including age, gender, pathological type, smoking index,weight loss,TNM staging,karnofsky(KPS) score and family history;the correlation between prognosis and Chinese medicine constitution types in NSCLC patients was studied by Logistic analysis. Results: Among 200 cases of patients, there were 29 cases with moderate constitution, accounting for 14.50% ; there were 20 cases with special intrinsic constitution,accounting for 10.00%;there were 22 cases with qi-depression constitution,accounting for 11.00%;there were 23 cases with dampness- heat constitution, accounting for 11.50% ; there were 20 cases with phlegm- dampness constitution, accounting for 20.00% ; there were 26 cases with blood stasis constitution, accounting for 13.00% ; there were 21 cases with yin- deficiency constitution, accounting for 10.50% ; there were 17 cases of yang- deficiency constitution, accounting for 8.50% ; there were 22 cases with qi- deficiency constitution, accounting for 11.00% . The factors including age,gender,pathological type,smoking index,KPS score and family history had no significant effect on Chinese medicine constitutions,there being no significance in the difference(P>0.05);TNM staging and weight loss had a significant effect on Chinese medicine constitutions, differences being significant(P<0.05). TNM staging was negatively correlated with moderate constitution, phlegm- dampness constitution and qi- deficiency constitution(P<0.05), and positively correlated with yin- deficiency constitution and yang- deficiency constitution(P<0.05). Weight loss was positively correlated with yin- deficiency constitution and negatively correlated with phlegm- dampness constitution(P<0.05). Conclusion:There is a certain correlation between TNM staging as well as weight loss and Chinese medicine constitutions in NSCLC patients. The higher the TNM stage is, the lower the probability of moderate constitution, phlegm- dampness constitution and qi-deficiency constitution,and the higher the probability of yin-deficiency constitution and yang-deficiency constitution. Among the patients with weight loss,there are more with yin-deficiency constitution and fewer with phlegmdampness constitution.

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郑秋霞,胡文雷,石灯汉,朱君华.非小细胞肺癌患者预后与中医体质类型相关性研究[J].新中医,2022,54(12):166-169

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  • 在线发布日期: 2022-06-22
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