Abstract：Objective：To observe the clinical effect of Shenqi Sichong tang combined with spinal manipulation for cervical spondylosis. Methods：A total of 102 cases of patients with cervical spondylosis were randomly divided into the control group and the observation group，with 51 cases in each group. The control group was treated with spinal manipulation，and the observation group was treated with Shenqi Sichong tang combined with spinal manipulation. Both groups were treated for four weeks. The clinical efficacy and incidence of adverse reactions were compared between the two groups. The Short- Form McGill Pain Questionnaire(SF- MPQ) scores and hemorrheology indexes before and after treatment in the two groups were compared. Results：The total effective rate was 90.20% in the observation group，higher than that of 74.51% in the control group(P＜0.05). After treatment，the scores of Pain Rating Index(PRI)，Visual Analogue Scale(VAS) and Present Pain Intensity (PPI) in the two groups were decreased when compared with those before treatment(P＜0.05)，and the scores of PRI，VAS and PPI in the observation group were lower than those in the control group(P＜0.05). After treatment， whole blood high shear viscosity， whole blood low shear viscosity and plasma viscosity in the observation group were decreased when compared with those before treatment，and were lower than those in the control group(P＜0.05). The incidence of adverse reactions in the observation group was 1.96% ， and there was no adverse reaction in the control group， there was no significant difference between the two groups(P＞0.05). Conclusion：Shenqi Sichong tang combined with spinal manipulation for cervical spondylosis can relieve pain and improve hemorrheology indexes with good clinical effects.