Abstract： Objective： To observe the clinical effect of the therapy of Zhichuang capsules combined with Mayinglong Shexiang Zhichuang ointment on hemorrhoids. Methods：A total of 100 patients with hemorrhoids were selected and divided into the treatment group and the control group according to random number table method， with 50 cases in each group. During the study，one case in the treatment group and two cases in the control group were dropped out. In the end，a total of 49 cases in the treatment group and 48 cases in the control group were included in the study. The control group was treated with Mayinglong Shexiang Zhichuang ointment， and the treatment group was treated with Zhichuang capsules combined with Mayinglong Shexiang Zhichuang ointment. Both groups were treated for four weeks and follow up for twelve months. The clinical effects， recurrence rates and symptom scores before and after treatment were compared between the two groups. Results：The total effective rate was 93.88% in the treatment group，higher than that of 83.33% in the control group (P＜0.05). After treatment，the scores of pain，bloody stool，hemorrhoids prolapse and anal discomfort in the two groups were decreased when compared with those before treatment(P＜0.05)，and the scores of the above four symptoms in the treatment group were lower than those in the control group(P＜0.05). The recurrence rates after six，nine and twelve months of follow-up were lower in the treatment group than those in the control group(P＜0.05). Conclusion：The therapy of Zhichuang capsules combined with Mayinglong Shexiang Zhichuang ointment has a better curative effect than the simple application of Mayinglong Shexiang Zhichuang ointment in the treatment of hemorrhoids，which can reduce the recurrence rate.