Abstract：Objective：To observe the clinical effect of the therapy of Zhishi Xiebai Guizhi tang and Xiao Xianxiong tang on stable angina pectoris of phlegm-heat internal obstruction type. Methods：A total of 80 patients with stable angina pectoris that met the inclusion and exclusion criteria were selected and divided into two groups according to the selected treatment methods. The 35 cases in the control group were treated with conventional western medicine treatment，and the 45 cases in the observation group were additionally treated with Zhishi Xiebai Guizhi tang and Xiao Xianxiong tang based on the treatment of the control group. Both groups were treated for four weeks. The Chinese medicine syndrome scores，Chinese medicine syndrome effects， angina pectoris effects and stopping- or- reducing usage rates of the nitroglycerin before and after treatment were compared between the two groups. Results：After treatment，the scores of chest pain and chest oppression and the total score of Chinese medicine syndrome in the observation group were lower than those in the control group，and the total effective rate of Chinese medicine syndrome was higher than that in the control group，differences being significant (P＜0.05). The total effective rate of angina pectoris was 86.67% in the observation group，higher than that of 65.71% in the control group，differences being significant(P＜0.05). The stopping-or-reducing usage rate of nitroglycerin in the observation group was higher than that in the control group，the difference being significant(P＜0.05). Conclusion：The therapy of Zhishi Xiebai Guizhi tang and Xiao Xianxiong tang can significantly improve the therapeutic effect，relieve the clinical symptoms and reduce the application of nitroglycerin in patients with stable angina pectoris of phlegm-heat internal obstruction type.