Abstract： Objective： To observe the clinical effect of umbilical application with Radix et Rhizoma Rhei combined with moxibustion for diabetic constipation with qi-yin deficiency syndrome. Methods：A total of 60 cases of patients with diabetic constipation with qi- yin deficiency syndrome were selected and divided into the control group and the observation group according to the random number table method， with 60 cases in each group. Both groups were given hypoglycemic treatment measures， dietary intervention and guidance on moderate exercise； the control group was given the oral administration with mosapride citrate tablets on the basis of routine hypoglycemic treatment，and the observation group was treated with umbilical application with Radix et Rhizoma Rhei and moxibustion based on routine hypoglycemic treatment. The changes in defecation interval，defecation time，defecation times per week and Clinical Scoring Scale for Constipation(CCS) were compared between the two groups before and after treatment. Clinical effects were evaluated. The recurrence of constipation was observed. Results： The total effective rate was 93.33% in the observation group， higher than that of 66.67% in the control group， the difference being significant(P＜0.05). After treatment， defecation interval and defecation time in the two groups were significantly decreased， and defecation interval and defecation time in the observation group were lower than those in the control group(P＜0.05)； defecation times per week in the two groups were increased when compared with those before treatment，and defecation times per week in the observation group were higher than those in the control group(P＜0.05). After treatment， CCS scores in the two groups were decreased when compared with those before treatment， and CCS score in the observation group was lower than that in the control group， the difference being significant(P＜0.05). The recurrence rate after drug withdrawal in the observation group was lower than that in the control group， the difference being significant(P＜0.05). Conclusion： Umbilical application with Radix et Rhizoma Rhei combined with moxibustion has a defined curative effect in the treatment of diabetic constipation with qi-yin deficiency syndrome. It can improve constipation symptoms and reduce the recurrence rate of constipation.