Abstract：Objective：To observe the analgesic effect of acupuncture-assisted anesthesia on lumbar fusion in the senile. Methods： A total of 64 cases of senile patients with lumbar fusion and divided into the control group and the experiment group according to the random number table method，with 32 cases in each group. During the operation，the control group was given general anesthesia， and the experiment group was given acupuncture therapy and general anesthesia. The differences of operation time， anesthetic time， anesthetic dosage and surgical bleeding between the two groups were compared. The changes of cognitive function evaluating by Mini-Mental State Scale(MMSE) and the time of Trail-Making Test (TMT) before and after operation as well as the incidence of postoperative adverse reactions were compared between the two groups. The differences of postoperative pain evaluated by Visual Analogue Scale(VAS) in the two groups were observed. Results： The operation time and anesthetic time in the experiment group were longer than those in the control group， anesthesia recovery time was earlier， and surgical bleeding was smaller， differences being significant(P＜0.05). Scores of MMSE in the two groups one day after the operation were decreased when compared with those before treatment，and the score in the experiment group was higher than that in the control group，differences being significant(P＜0.05). The time of TMT in the two groups one day after the operation was prolonged when compared with that before treatment，and the time in the experiment group was shorter than that in the control group， differences being significant(P＜0.05). The score of postoperative VAS in the experiment group was smaller than that in the control group，the difference being significant(P＜ 0.05). The incidence of adverse reactions was 21.88% in the experiment group and 53.13% in the control group， the difference being significant(P＜0.05). Conclusion：Acupuncture-assisted anesthesia has a good analgesic effect after lumbar fusion in the senile. It can help shorten the recovery time from anesthesia， improve cognitive function of patients， and reduce the incidence of adverse reactions.