Abstract：This paper introduces Prof. XIE Changsheng's clinical experience in differentiating and treating breast cancerrelated lymphedema. Starting from the principle that fluids and blood are from the same source and based on the theory of "blocked blood circulation resulting in water retention"，Prof. XIE Changsheng believes that "blocked blood circulation" is the intermediate link of breast cancer- related lymphedema. The disease occurs because spleen and qi are deficient， and the blood stagnates so stasis is generated；and the static blood retains and generates fluid retention which overflows to the skin surface and leads to the symtom of swelling. Therefore，boosting qi and invigorating blood，and inducing diuresis to alleviate edema are the main treatment methods. The specific methods are boosting qi and supplementing deficiency， and taking spleen as the key；invigorating blood and dissolving stasis ， and dissipating old hydro-stagnation ； harmonizing the triple energizers ， and inducing diuresis to alleviate edema； clearing and relieving residual poison， and dispelling pathogen to protect healthy qi. In short， the emphasis on supplementing and boosting the spleen and qi can achieve the therapeutic purpose to eliminate the swelling by the normal qi flow，blood circulation and water transportation.