Abstract：Objective：To observe the clinical effect of Yiqi Huoxue method combined with western medicine for ascites due to cirrhosis of qi deficiency and blood stasis type. Methods：A total of 90 cases of patients with ascites due to cirrhosis of qi deficiency and blood stasis type were selected and divided into the control group and the experiment group according to the random number table method，with 45 cases in each group respectively. The control group was given symptomatic treatment of western medicine，and the experiment group was additionally treated with Yiqi Huoxue method based on the treatment of the control group. Both groups were treated for one month. The 24- hour urine volume ， body mass ， abdominal circumference and liver function indexes in the two groups were compared before and after treatment. The clinical effects in the two groups were compared，and the adverse reactions were recorded. Results：The total effective rate was 91.11% in the experiment group，higher than that of 75.56% in the control group(P＜0.05). After treatment，24-hour urine volume in the two groups was increased when compared with that before treatment(P＜0.05)， body mass decreased(P＜0.05)， and abdominal circumference smaller(P＜0.05)；24-hour urine volume in the experiment group was more than that in the control group(P＜0.05)， body mass lower(P＜0.05)， and abdominal circumference smaller(P＜0.05). After treatment， levels of alanine aminotransferase(ALT)， aspartate aminotransferase(AST) and total bilirubin(TBil) in the two groups were decreased when compared with those before treatment(P＜0.05)，and levels of Alb were increased(P＜0.05)；levels of ALT，AST and TBil in the experiment group were lower than those in the control group(P＜0.05)，and Alb level was higher(P＜0.05). During treatment， there was no severe adverse reaction in the two groups. Conclusion： Yiqi Huoxue method combined with western medicine for ascites due to cirrhosis of qi deficiency and blood stasis type can effectively enhance diuretic effect， relieve clinical symptoms，and improve the liver function，with high safety.