Abstract： Objective： To observe the clinical effect of modified Buyang Huanwu tang assisting western medicine for cerebral infarction. Methods：A total of 96 cases of patients with cerebral infarction were selected as research objects，and were divided into the control group and the observation group according to the random number table method，with 48 cases in each group. The control group was treated with routine western medicine， and the observation group was additionally treated with modified Buyang Huanwu tang based on the treatment of the control group. The levels of C-reactive protein and D- dimer as well as hemorheology indexes before and after treatment in the two groups were detected， and the clinical effects in the two groups were evaluated. Results：The total effective rate was 97.92% in the observation group and 81.25% in the control group，the difference being significant (P＜0.05). Before treatment，there was no significant difference being found in the comparison of the levels of C-reactive protein and D-dimer between the two groups(P＞0.05). After treatment， the levels of D-dimer and C-reactive protein in the two groups were decreased when compared with those before treatment (P＜0.05)，and the levels of D- dimer and C- reactive protein in the observation group were lower than those in the control group (P＜0.05). Before treatment， there was no significant difference being found in the comparison of whole blood viscosity， plasma viscosity and erythrocyte sedimentation rates between the two groups(P＞0.05). After treatment， the whole blood viscosity， plasma viscosity and erythrocyte sedimentation rates in the two groups were decreased when compared with those before treatment(P＜0.05)， and the whole blood viscosity， plasma viscosity and erythrocyte sedimentation rate in the observation group were lower than those in the control group(P＜0.05). Conclusion：The therapy of modified Buyang Huanwu tang assisting western medicine for cerebral infarction has a significant curative effect， and can effectively improve blood flow pattern and reduce the levels of serum C-reactive protein and D-dimer.