补阳还五汤加减辅助常规西药治疗脑梗死临床研究
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R743.3

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Clinical Study on Modified Buyang Huanwu Tang Assisting Western Medicine for Cerebral Infarction
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    摘要:

    目的:观察补阳还五汤加减辅助常规西药治疗脑梗死的临床疗效。方法:选择96 例脑梗死患者作为研究对象,按随机数字表法分为对照组和观察组各48 例。对照组给予常规西药治疗,观察组在对照组基础上给予补阳还五汤加减治疗。检测2 组治疗前后C-反应蛋白、D-二聚体水平以及血液流变学指标,并评价2 组临床疗效。结果:观察组总有效率为97.92%,对照组为81.25%,2 组比较,差异有统计学意义(P<0.05)。治疗前,2 组D-二聚体、C-反应蛋白水平比较,差异无统计学意义(P>0.05)。治疗后,2 组D-二聚体、C-反应蛋白水平较治疗前降低(P<0.05),且观察组D-二聚体、C-反应蛋白水平均低于对照组(P<0.05)。治疗前,2 组全血黏度、血浆黏度以及红细胞沉降率比较,差异无统计学意义(P>0.05)。治疗后,2 组全血黏度、血浆黏度以及红细胞沉降率较治疗前降低(P<0.05),且观察组全血黏度、血浆黏度以及红细胞沉降率均低于对照组(P<0.05)。结论:补阳还五汤加减辅助常规西药治疗脑梗死疗效显著,可有效改善血流状态,降低血清C-反应蛋白、D-二聚体水平。

    Abstract:

    Abstract: Objective: To observe the clinical effect of modified Buyang Huanwu tang assisting western medicine for cerebral infarction. Methods:A total of 96 cases of patients with cerebral infarction were selected as research objects,and were divided into the control group and the observation group according to the random number table method,with 48 cases in each group. The control group was treated with routine western medicine, and the observation group was additionally treated with modified Buyang Huanwu tang based on the treatment of the control group. The levels of C-reactive protein and D- dimer as well as hemorheology indexes before and after treatment in the two groups were detected, and the clinical effects in the two groups were evaluated. Results:The total effective rate was 97.92% in the observation group and 81.25% in the control group,the difference being significant (P<0.05). Before treatment,there was no significant difference being found in the comparison of the levels of C-reactive protein and D-dimer between the two groups(P>0.05). After treatment, the levels of D-dimer and C-reactive protein in the two groups were decreased when compared with those before treatment (P<0.05),and the levels of D- dimer and C- reactive protein in the observation group were lower than those in the control group (P<0.05). Before treatment, there was no significant difference being found in the comparison of whole blood viscosity, plasma viscosity and erythrocyte sedimentation rates between the two groups(P>0.05). After treatment, the whole blood viscosity, plasma viscosity and erythrocyte sedimentation rates in the two groups were decreased when compared with those before treatment(P<0.05), and the whole blood viscosity, plasma viscosity and erythrocyte sedimentation rate in the observation group were lower than those in the control group(P<0.05). Conclusion:The therapy of modified Buyang Huanwu tang assisting western medicine for cerebral infarction has a significant curative effect, and can effectively improve blood flow pattern and reduce the levels of serum C-reactive protein and D-dimer.

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程桂兰.补阳还五汤加减辅助常规西药治疗脑梗死临床研究[J].新中医,2022,54(7):42-45

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  • 在线发布日期: 2022-04-12
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