Abstract: Objective: To observe the clinical effect of the therapy of acupuncture at Beishu points combined with diaphragmatic pacing on respiratory dysfunction after stroke. Methods:A total of 60 patients with respiratory dysfunction after stroke were selected and divided into the control group and the observation group according to the random number table method, with 30 cases in each group. The control group was treated with external diaphragm pacemaker(EDP), and the observation group was additionally treated with acupuncture at Beishu points. Both groups were treated for four weeks. Before and after treatment, blood gas analysis indexes, diaphragmatic motion, diaphragm thickness, lung function and quality of life in the two groups were compared. Results:After treatment,the partial pressure of carbon dioxide(PaCO2) in both groups was decreased when compared with that before treatment(P<0.05),and the partial pressure of oxygen(PaO2) and oxygenation index(OI) were increased(P<0.05);the PaCO2 in the observation group was lower than that in the control group(P<0.05), and the PaO2 and OI were higher(P<0.05). After treatment, the diaphragmatic motion and diaphragm thickness in the two groups were increased when compared with those before treatment(P<0.05), and the above two indexes in the observation group were higher than those in the control group(P<0.05). After treatment,forced vital capacity (FVC),percentage of maximum expiratory volume in the first second to the expected value(FEV1%pred),and percentage of maximum expiratory volume in the maximum minute ventilation(MMV%pred) in both groups were increased when compared with those before treatment(P<0.05),and the above three indexes in observation group were higher than those in control group(P<0.05). After treatment,the scores of Barthel Index(BI),physical function,psychological function,social function and material life in the two groups were increased when compared with those before treatment(P<0.05), and the above scores in the observation group were higher than those in the control group(P<0.05). Conclusion: The therapy of acupuncture at Beishu points combined with diaphragm pacing can effectively improve the blood gas analysis indexes, diaphragm motion,lung function and quality of life of patients with respiratory dysfunction after stroke.