三金韦蔚汤结合耳穴压豆治疗肾结石体外震波碎石术后临床研究
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Clinical Study on Sanjin Weiwei Tang Combined with Auricular Point Pressing with Beans for Kidney Calculi After Extracorporeal Shock Wave Lithotripsy
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    摘要:

    目的:观察在常规用药基础上应用三金韦蔚汤结合耳穴压豆治疗肾结石体外震波碎石术(ESWL) 后患者的临床效果。方法:选取88 例肾结石湿热瘀滞证患者,按随机数字表法分为研究组、对照组各44 例。2 组患者均行ESWL 治疗,术后常规对症处理。对照组术后给予坦索罗辛缓释胶囊治疗,研究组给予三金韦蔚汤结合耳穴压豆治疗。2 组均治疗4 周。比较2 组的中医证候积分、转归时间、排石情况、肾功能指标[尿素氮(BUN)、β2-微球蛋白(β2-MG)、血肌酐(SCr)]以及临床疗效。结果:治疗4 周,研究组临床疗效总有效率97.73%,高于对照组的79.55%,差异有统计学意义(P<0.01)。2 组小便涩痛、排尿中断、小便频急、腰腹部疼痛、尿血或尿色赤黄评分均较治疗前减少,研究组5 项评分均低于对照组,差异均有统计学意义(P<0.01)。研究组腰腹疼痛减轻时间、可视血尿消失时间均较对照组缩短,首次排石时间较对照组提前,结石排出率及排净率均高于对照组,差异均有统计学意义(P<0.01,P<0.05)。术后3 d、术后2 周,2 组BUN、β2-MG、SCr 水平均较术前升高(P<0.05);术后4 周,对照组BUN、β2-MG、SCr 水平均较术前升高(P<0.05),而研究组3 项指标值与术前比较,差异均无统计学意义(P>0.05)。术后3 d,研究组BUN、β2-MG、SCr 水平均低于对照组(P<0.05);术后2 周,2 组BUN、β2-MG、SCr 水平均较术后3 d 降低(P<0.05),研究组3 项指标值均低于对照组(P<0.05);术后4 周,2 组BUN、β2-MG、SCr 水平均较术后3 d、术后2 周降低(P<0.05),研究组3 项指标值均低于对照组(P<0.05)。结论:三金韦蔚汤结合耳穴压豆可有效改善肾结石ESWL 术后患者的中医证候,促进结石排出,提高临床疗效,同时有利于保护肾功能。

    Abstract:

    Abstract:Objective:The clinical effect of the therapy of Sanjin Weiwei tang combined with auricular point pressing with beans based on routine administration on kidney calculi after extracorporeal shock wave lithotripsy(ESWL) was observed. Methods:A total of 88 patients with kidney calculi with dampness-heat stasis and stagnation syndrome were selected and divided into the study group and the control group according to the random number table method, with 44 cases in each group. Both groups were treated with ESWL,and routine symptomatic treatment was performed after operation. The control group was treated with tamsulosin hydrochloride sustained release capsules after surgery,and the study group was treated with Sanjin Weiwei tang combined with auricular point pressing with beans. Both groups were treated for four months. The Chinese medicine syndrome scores,recovery time,stone expelling,kidney function indexes,including blood urea nitrogen (BUN),β2-microglobulin(β2-MG) and serum creatinine(SCr),and clinical effects in the two groups were compared. Results: After four weeks of treatment,the total clinical effective rate was 97.73% in the study group,higher than that of 79.55% in the control group, the difference being significant(P<0.01). The scores of difficult and painful urination, urination interruption, frequent urination, pain in waist and abdomen, and bloody or dark urine in the two groups were decreased when compared with those before treatment, and the above five scores in the study group were lower than those in the control group,differences being significant(P<0.01). The pain relief time of waist and abdomen and the disappearance time of visual boody urine in the study group were shorter than those in the control group, the first stone expelling time was earlier,and the stone expelling rate and clean rate were higher,differences being significant(P<0.05). Three days and two weeks after operation,the levels of BUN,β2- MG and SCr in the two groups were increased when compared with those before surgery, Three days and two weeks after surgery, the levels of BUN, β2- MG and SCr in the two groups were increased when compared with those before surgery(P<0.05). When compared with those before surgery, levels of BUN, β2-MG and SCr in the two groups were increased four weeks after surgery(P<0.05), and the comparison of the three levels in the study group before surgery and four weeks after surgery showed no significance in differences(P>0.05). Three days after surgery, levels of BUN, β2-MG and SCr in the study group were lower than those in the control group(P<0.05). Two weeks after surgery, levels of BUN, β2-MG and SCr in the two groups were decreased when compared with those three days after surgery(P<0.05), and the three levels in the study group were lower than those in the control group(P<0.05). Four weeks after surgery, levels of BUN, β2-MG and SCr in the two groups were decreased when compared with those three days and two weeks after surgery(P<0.05), and the three levels in the study group were lower than those in the control group (P<0.05). Conclusion:The therapy of Sanjin Weiwei tang combined with auricular point pressing with beans can effectively alleviate the Chinese medicine syndromes of patients with kidney calculi after ESWL, promote the stone expelling,improve the clinical effects,and protect the kidney function.

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赖立贵,项晓皑,何少青.三金韦蔚汤结合耳穴压豆治疗肾结石体外震波碎石术后临床研究[J].新中医,2022,54(4):84-89

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  • 在线发布日期: 2022-02-24
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