调免养血方联合西药治疗肾虚血瘀型复发性流产临床研究
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R714.21

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浙江省陈颖异名老中医专家传承工作室(浙中医药[2017]28号);温州市科技局项目(Y20180819)


Clinical Study on Tiaomian Yangxue Prescription Combined with Western Medicine for Recurrent Spontaneous Abortion of Kidney Deficiency and Blood Stasis Type
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    摘要:

    目的:观察调免养血方联合西药治疗肾虚血瘀型复发性流产的临床疗效。方法:选取60 例肾虚血瘀型复发性流产孕妇,按随机数字表法分为对照组和观察组各30 例。对照组给予黄体酮+低分子肝素治疗,观察组在对照组基础上加用调免养血方治疗。比较2 组临床疗效,观察治疗前后中医证候评分、激素水平、妊娠成功率及不良反应情况。结果:观察组总有效率为90.00%,高于对照组70.00%,差异有统计学意义(P<0.05)。孕8 周时,2 组各项中医证候评分均低于治疗前,且观察组各项评 分均低于对照组(P<0.05)。孕8 周时,2 组孕激素(P)、血清绒毛膜促性腺激素(HCG) 及雌二醇(E2) 水平高于治疗前,且观察组激素水平高于对照组(P<0.05)。观察组宫内妊娠成功率为90.00%,高于对照组73.33%,差异有统计学意义(χ2=4.320,P=0.038)。观察组不良反应发生率(6.67%) 低于对照组(26.67%)(P<0.05)。结论:调免养血方联合西药治疗复发性流产临床疗效显著,能改善孕妇临床症状,提高激素水平和妊娠成功率,安全可靠。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Tiaomian Yangxue prescription combined with western medicine for recurrent spontaneous abortion of kidney deficiency and blood stasis type. Methods: A total of 60 cases of pregnant women with recurrent spontaneous abortion of kidney deficiency and blood stasis type were divided into the control group and the observation group according to the random number table method,with 30 cases in each group. The control group was treated with progesterone and low molecular weight heparin, and the observation group was additionally treated with Tiaomian Yangxue prescription based on the treatment of the control group. The clinical effects in the two groups were compared. Before and after treatment,Chinese medicine syndrome scores,hormone levels,pregnancy success rate and adverse reactions were observed. Results:The total effective rate was 90.00% in the observation group,higher than that of 70.00% in the control group, the difference being significant(P<0.05). At eight weeks of pregnancy, Chinese medicine syndrome scores in the two groups were lower than those before treatment,and the scores in the observation group were lower than those in the control group(P<0.05). At eight weeks of pregnancy,the levels of progesterone(P),human chorionic gonadotropin(HCG) in serum and estrogen(E2) in the two groups were higher than those before treatment, and the above hormone levels in the observation group were higher than those in the control group(P<0.05). The success rate of intrauterine pregnancy was 90.00% in the observation group, higher than that of 73.33% in the control group, the difference being significant(χ 2=4.320,P=0.038). The incidence of adverse reactions was 6.67% in the observation group,lower than that of 26.67% in the control group(P<0.05). Conclusion: Tiaomian Yangxue prescription combined with western medicine has a significant clinical effect in treating recurrent spontaneous abortion,and can improve clinical symptoms,hormone levels and pregnancy success rate,which is safe and reliable.

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周笑梅,钱海默,陈颖异.调免养血方联合西药治疗肾虚血瘀型复发性流产临床研究[J].新中医,2022,54(3):126-129

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  • 在线发布日期: 2022-02-14
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