Abstract：This paper introduces MOU Chonglin's clinical views on the use of Radix et Rhizoma Ginseng in the treatment of six- meridian in Shanghan Lun. MOU believes that if multiple treatments of eliminating pathogens are not effective for severe cold damage，the use of Radix et Rhizoma Ginseng should be taken into consideration to reinforce the healthy qi and eliminate the pathogenic factors；in particular，patients with prodrome of collapse should be treated with Radix et Rhizoma Ginseng immediately. For patients with cold damage，Radix et Rhizoma Ginseng，which can boost qi and preserve yin as well as expel pathogens and prevent any pathological changes， should be used in formulas that are prescribed according to syndromes. For example，for patients with greater yang diseases，Radix et Rhizoma Ginseng can boost qi and release the exterior； for those with lesser yang diseases， it can reinforce the healthy qi and expel pathogens； for yang brightness disease syndrome，it can boost qi and discharge heat；for yang brightness bowel syndrome，it can supplement deficiency and unblock the bowels； for greater yin diseases， it can fortify the spleen and harmonize the center； for lesser yang diseases， it can boost qi and rescue from desertion； for reverting yin diseases， it can rescue from desertion and stop diarrhea.