Abstract：Objective：To observe the effect of compound Danshen dripping pills on myocardial blood supply in patients with myocardial ischemia of coronary heart disease during selective surgery. Methods：A total of 82 patients with myocardial ischemia of coronary heart disease during selective surgery were randomly divided into the control group and the observation group according to the random number table， with 41 cases in each group. Both groups were treated with percutaneous coronary intervention(PCI)； the control group was treated with metoprolol tartrate tablets， and the observation group was treated with compound Danshen dripping pills. The systolic blood pressure/diastolic blood pressure(SBP/DBP)， heart rate systolic blood pressure product(RPP)，left ventricular ejection fraction(LVEF)，stroke output(SV) and peak mitral valve velocity ratio(E/A) were compared between the two groups before and after surgery. Results： Before surgery， there was no significant difference in the levels of SBP，DBP，RPP and SaO2 between the two groups(P＞0.05). After surgery，the levels of SBP，DBP and oxygen saturation(SaO2) in the two groups were increased，while the RPP level decreased；the levels of SBP，DBP and SaO2 in the observation group were higher than those in the control group，while the RPP level was lower， differences being significant(P＜0.05). Before surgery，there was no significant difference in the levels of LVEF，SV and E/A between the two groups(P＞0.05). After surgery，the levels of LVEF，SV and E/A in the two groups were higher than those before treatment， and the above three levels in the observation group were significantly higher than those in the control group， differences being significant(P＜0.05). Conclusion： Compound Danshen dripping pills can effectively improve blood pressure and heart rate and reduce the risks in patients with myocardial ischemia of coronary heart disease during selective surgery.