Abstract：Objective：To observe the effect of point stimulation by electro-acupuncture device combined with emotional nursing on self-efficacy，gastrointestinal function and quality of life in patients in perioperative period of stomach neoplasms. Methods： A total of 80 cases of patients with stomach neoplasms who receive operative treatment were selected as the study subjects and divided into the control group and the observation group according to the random number table method， with 40 cases in each group. The control group was given routine nursing and emotional nursing，and the observation group was additionally given nursing with point stimulation by electro-acupuncture device based on the nursing intervention of the control group. After the nursing of perioperative period， scores of General Self- Efficacy Scale(GSES)， Rosenberg Self- Esteem Scale(RSES) and the Short Form 36 Health Survey(SF-36)，as well as the status of gastrointestinal function(the time of first anal exhaust and defecation， the recovery time of bowel sound) were observed and compared between the two groups. Results：After nursing intervention，scores of GSES and RSES in the two groups were increased when compared with those before intervention(P＜0.05)，and the two scores in the observation group were higher than those in the control group(P＜0.05). After nursing intervention，the time of first anal exhaust and defecation and the recovery time of bowel sound in the observation were shorterthan those in the control group， the difference being significant(P＜0.05). After nursing intervention， scores of mental health， emotional role， social function， vitality， bodily pain， physiological role and physiological function in the two groups were increased when compared with those before nursing(P＜0.05)，and the scores in the observation group were higher than those in the control group(P＜0.05). Conclusion： The intervention of point stimulation by electro- acupuncture device combined with emotional nursing on patients in perioperative period of stomach neoplasms can effectively enhance their self-efficacy，and promote the recovery of gastrointestinal function and improve the quality of life.