补中益气颗粒联合双歧杆菌三联活菌胶囊治疗慢性腹泻临床研究
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Clinical Study on Buzhong Yiqi Granules Combined with Bifidobacterium Triple Viable Capsules for Chronic Diarrhea
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    摘要:

    目的:观察补中益气颗粒联合双歧杆菌三联活菌胶囊治疗慢性腹泻的临床疗效。方法:选取80 例慢性腹泻患者,按不同治疗方法分成观察组和对照组,每组40 例。对照组给予双歧杆菌三联活菌胶囊治疗,观察组在对照组基础上给予补中益气颗粒治疗,2 组均连续治疗3 周。比较2 组临床疗效及治疗前后T 淋巴细胞亚群水平。结果:观察组总有效率为95.0%,高于对照组的77.5%(P<0.05)。治疗后,2 组血清CD8+水平均较治疗前降低(P<0.05),CD4+/CD8+均较于治疗前升高(P<0.05);观察组血清CD8+水平低于对照组(P<0.05),CD4+/CD8+高于对照组(P<0.05);2 组血清CD4+水平比较,差异无统计学意义(P>0.05)。结论:补中益气颗粒联合双歧杆菌三联活菌胶囊治疗慢性腹泻可提高临床疗效,有效调节患者的免疫功能。

    Abstract:

    Abstract:Objective:To observe the clinical effect of Buzhong Yiqi granules combined with bifidobacterium triple viable capsules for chronic diarrhea. Methods:A total of 80 cases of patients with chronic diarrhea were selected and divided into the observation group and the control group according to different treatment methods, with 40 cases in each group. The control group was treated with bifidobacterium triple viable capsules,and the observation group was additionally treated with Buzhong Yiqi granules based on the treatment of the control group. Both groups were treated for three weeks. The levels of T lymphocyte subsets before and after treatment as well as the clinical effects in the two groups were compared. Results:The total effective rate was 95.0% in the observation group, higher than that of 77.5% in the control group(P<0.05). After treatment,the levels of CD8+ in serum in the two groups were decreased when compared with those before treatment(P< 0.05),and CD4+/CD8+ in the two groups were increased when compared with those before treatment(P<0.05);serum CD8+ level in the observation group was lower than that in the control group(P<0.05), and CD4 +/CD8 + was higher(P<0.05). There was no significant difference being found in the comparison of serum CD4 + levels between the two groups(P>0.05). Conclusion:The therapy of Buzhong Yiqi granules combined with bifidobacterium triple viable capsules for chronic diarrhea can improve the clinical effect,and effectively regulate the immune function of patients.

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徐立华,周晓峰.补中益气颗粒联合双歧杆菌三联活菌胶囊治疗慢性腹泻临床研究[J].新中医,2021,53(24):43-45

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  • 在线发布日期: 2021-12-27
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