Abstract：Objective：To observe the clinical effect of auricular point pressing with beans combined with point application of Radix et Rhizoma Rhei at Shenque point on the treatment of multiple myeloma complicated with constipation of qi deficiency type on the basis of conventional medical measures. Methods：A total of 204 patients with multiple myeloma with constipation of qi deficiency type were divided into the control group and the observation group，102 cases in each group. Both groups were given routine treatment and nursing measures to prevent constipation，and treated with point application of Radix et Rhizoma Rhei at Shenque point，and the observation group was additionally treated with auricular point pressing with beans. The treatment course of both groups was 14 days. The scores of defecation index， symptoms of qi deficiency syndrome and Patient-Assessment of Constipation Quality of Life(PAC-QOL) before treatment and 14 days after treatment were compared between the two groups，and the effect and incidence of adverse reactions after treatment were compared. Results：After 14 days of treatment，the therapeutic effect in the observation group was better than that in the control group (P＜0.05). The scores of defecation difficulty，defecation time，defecation interval and fecal morphology in both groups were decreased when compared with those before treatment(P＜0.01)，and the above four scores in the observation group were lower than those in the control group(P＜0.01). The scores of defecation weakness，abdominal dull pain，lack of strength and unwillingness to speak，and poor appetite in both groups were decreased when compared with those before treatment(P＜ 0.01)，and the scores of the above four symptoms in the observation group were lower than those in the control group(P＜ 0.01). The scores of physiology，society and psychology，worry and anxiety，and satisfaction in PAC- QOL in both groups were decreased when compared with those before treatment(P＜0.01)，and the above scores in the observation group were lower than those in the control group(P＜0.01). There was no significant difference in the incidence of adverse reactions between the two groups(P＞0.05). Conclusion：On the basis of conventional medical care measures，the therapy of auricular point pressing with beans and point application of Radix et Rhizoma Rhei at Shenque point has a significant effect on patients with multiple myeloma complicated with constipation of qi deficiency type in improving constipation， and can effectively improve the quality of life.