名医治疗肺癌气阴两虚兼痰热阻滞证用药规律研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R734.2

基金项目:

山西省卫计委项目(2017133);山西中医药大学科技创新培育计划项目(2019PY-022)


Study on Administration Rules of Famous Doctors in Treating Lung Cancer with Dual Deficiency of Qi and Yin and Obstruction of Phlegm-Heat Syndrome
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:利用中医传承辅助系统V2.5,分析名医治疗肺癌气阴两虚兼痰热阻滞证的用药规律,并挖掘发现新处方。方法:收集1996 年1 月—2019 年12 月期间中国知网收录的省级以上名医治疗肺癌的期刊文献,将符合纳入标准的方药录入中医传承辅助系统V2.5,利用该软件进行药物频次、关联规则及熵聚类分析。结果:筛选出符合纳入标准的方剂共126 首,涉及中药272 味。其中,补气补阴常用药物有黄芪、白术、麦冬,清热散结常用白花蛇舌草,化痰止咳平喘常用浙贝母,利水渗湿常用茯苓,理气常用陈皮。通过关联规则分析得到药对组合37 对,规则组合22 条,以及由以六君子汤加黄芪、薏苡仁、浙贝母、麦冬、北沙参、白花蛇舌草等药物组成的网络图。通过熵聚类分析得到36 对药物核心组合,18 首新处方。结论:名医治疗肺癌气阴两虚兼痰热阻滞证的用药规律分析结果体现了“标本兼治”的治疗思路。补虚以补气阴两虚为主,其次为补血、补阳;泻实以治痰湿、血瘀、热毒为主,其次为止咳喘、理气机。

    Abstract:

    Abstract:Objectives:Traditional Chinese medicine inheritance support system V2.5 was used to analyze the medication rules of famous doctors in the treatment of lung cancer with dual deficiency of qi and yin and obstruction of phlegm- heat syndrome, so as to discover new prescriptions. Methods: The periodical literature of famous doctors at or above the provincial level about the treatment of lung cancer collected by CNKI from January 1996 to December 2019 was collected. The prescriptions that met the inclusion criteria were imported into the traditional Chinese medicine inheritance support system V2.5. The software was used for analyzing usage frequency of medicine,association rules and entropy clustering. Results:A total of 126 prescriptions meeting the inclusion criteria were selected, involving 272 kinds of Chinese medicines. Among them,Radix Astragali,Rhizoma Atractylodis Macrocephalae and Radix Ophiopogonis are commonly used for tonifying qi and yin; Herba Hedyotis Diffusae is commonly used for clearing heat and dissipating binds; Bulbus Fritillariae Thunbergii is commonly used for resolving phlegm,suppressing cough and calming panting;Poria is commonly used for inducing diuresis to drain dampness,and Pericarpium Citri Reticulatae is commonly used for regulating qi. Through association rule analysis,a total of 37 pairs of couplet medicines and 22 combinatorial rules were obtained,as well as the network diagram composed of Liujunzi tang and medicines such as Radix Astragali, Semen Coicis, Bulbus Fritillariae Thunbergii, Radix Ophiopogonis, Radix Glehniae,and Herba Hedyotis Diffusae. A total of 36 pairs of core combinations of medicines and 18 new prescriptions were obtained by entropy cluster analysis. Conclusion:The analysis results of administration rules of famous doctors in the treatment of lung cancer with dual deficiency of qi and yin and obstruction of phlegm- heat syndrome reflect the treatment idea of “treating both tip and root”. The tonification of deficiency is mainly to tonify the dual deficiency of qi and yin, followed by tonifying blood and yang;excess purgation is mainly to treat phlegm- dampness,blood stasis and heat toxin, followed by suppressing cough,calming panting,and regulating qi.

    参考文献
    相似文献
    引证文献
引用本文

常佳婧,王晞星,何院生.名医治疗肺癌气阴两虚兼痰热阻滞证用药规律研究[J].新中医,2021,53(22):125-129

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-11-26
  • 出版日期: