Abstract：Objectives：To observe the curative effect of retention enema with modified Dachengqi tang combined with hot package ironing for intestinal obstruction after subtotal gastrectomy based on the routine therapy. Methods： A total of 100 cases of patients with intestinal obstruction after subtotal gastrectomy were selected as the observational subjects and divided into the control group and the observation group according to different treatment methods， with 50 cases in each group. Both groups were treated with routine therapy，and the observation group was additionally intervened with retention enema with modified Dachengqi tang combined with hot package ironing. Both groups were treated for two weeks. The clinical effects，the relief time of abdominal distension and pain as well as nausea and vomiting，and the recovery time of defecation as well as exhaust in the two groups were compared. Before treatment and after two weeks of treatment，the Chinese medicine syndrome scores were evaluated，and the levels of serum inflammatory factors including interleukin-6(IL-6)， C- reactive protein(CRP) and tumor necrosis factor- α(TNF- α) were detected. Results：After two weeks of treatment，the total effective rate was 90.0% in the observation group， higher than of 76.0% in the control group， the difference being significant(P＜0.05). The Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P＜0.05)， and the Chinese medicine syndrome score in the observation group was lower than that in the control group(P＜0.05). The relief time of abdominal distension and pain as well as nausea and vomiting，and the recovery time of defecation as well as exhaust in the observation group were shortened when compared with those in the control group(P＜0.05). The levels of TNF- α，IL- 6 and CRP in the two groups were decreased when compared with those before treatment(P＜0.05)， and the three indexes in the observation group were lower than those in the control group(P＜0.05). Conclusion：Based on routine therapy，retention enema with modified Dachengqi tang combined with hot package ironing has good clinical effect in treating patients with intestinal obstruction after subtotal gastrectomy，can accelerate the alleviation of symptoms and promote the recovery of postoperative intestinal function， whose mechanism may be related to the regulation of inflammatory factors in patients.