Abstract：This paper explains Professor MAO Dexi's commonly used Sanwei prescription for hypertension. Erye Jiangya tang， Xiaotianma Gouteng yin， Queyu Daozhi powder， Shuangzhi Chubi tang， Toutong Sanwei prescription and hypertension powder are the commonly used Sanwei prescription for the treatment of hypertension by Professor MAO Dexi. Erye Jiangya tang， composed of Folium Eucommiae， Folium Mori and Radix Achyranthis Bidentatae， is applied for hypertension with upper excess and lower deficiency syndrome； Xiaotianma Gouteng yin， composed of Rhizoma Gastrodiae，Ramulus Uncariae Cum Uncis and Concha Haliotidis，is the first choice for treating liver wind harassing the upper body and blockage of collateral vessel；Queyu Daozhi powder，composed of Fructus Leonuri，Radix Achyranthis Bidentatae and Radix Cyathulae， can play a role in treating disease in the upper body from the lower one， clearing head wind and improving vision，unblocking the orifices and activating blood；Shuangzhi Chubi tang，composed of Herba Siegesbeckiae， Ramulus Mori and Ramulus Cinnamomic， plays a role in dredging meridians， dispelling wind and eliminating bi； Toutong Sanwei prescription，composed of Fructus Leonuri，Fructus Viticis and Semen Cassiae，plays a role in clearing liver heat and improving vision，scattering wind and invigorating blood as well as clearing head and eyes；hypertension powder，composed of Rhizoma Gastrodiae powder， Radix et Rhizoma Notoginseng powder and Semen Cassiae powder， is applied for hypertension and cerebral infarction with blood stasis indication.