Abstract： Objective： To observe the clinical effect of acupuncture combined with medication for polycystic ovarian syndrome(PCOS) complicated with luteinized unruptured follicle syndrome(LUFS). Methods： A total of 60 cases of patients with PCOS complicated with LUFS in accordance with the inclusion criteria were selected and randomly divided into two groups， 30 cases in each group. The western medicine group was treated with clomiphene and injection with chorionic gonadotropin； the acupuncture- medicine group was additionally treated with Chinese herbal medicine and acupuncture of Bushen Tiaozhou method based on the treatment of the western medicine group. Both groups were treated for three months. During the period， the advantage ovum and the endometrial receptivity were observed and compared； the contents of progesterone(P)，estradiol(E2) and luteinizing hormone(LH) were detected；the ovulation rate and the pregnancy rate in the two groups were compared. Results： After three months of treatment， the endometrial thickness in the two groups was significantly increased when compared with that before treatment； E2， LH and P were increased； PI and RI were significantly decreased，differences being significant(P＜0.05)；the endometrial thickness and the contents of E2，LH and P in the acupuncture-medicine group were higher than those in the western medicine group，and RI and PI were lower，the difference being significant(P＜0.05)； the ovulation rate was 80.0% in the acupuncture- medicine group and 60.0% in the western medicine group； the pregnancy rate was 56.7% in the acupuncture group and 36.7% in the western medicine group，differences being significant(P＜0.05). Conclusion：The therapy of acupuncture combined with medication for PCOS complicated with LUFS can promote the recovery of endometrial function and ovulation function，and improve the success rate of pregnancy in patients with infertility caused by ovulation disorder.