Abstract：Objective：To observe the effect of Chinese medicine emotional nursing on negative emotions and quality of life in patients undergoing operation for rectal cancer. Methods： A total of 112 cases of patients undergoing operation for rectal cancer were selected and divided into the control group and the study group according to the single or double number of their admission，56 cases in each group. The control group was given routine nursing，and the study group was additionally treated with Chinese medicine emotional nursing based on the treatment of the control group. Both groups were intervened until one month after operation. The nursing satisfaction， and the scores of Short Form- 36 Health Survey(SF- 36)， Selfrating Depression Scale(SDS) and Self- rating Anxiety Scale(SAS) in the two groups were compared. Results： The nursing satisfaction was 96.43% in the study group， higher than that of 83.93% in the control group(P＜0.05). After nursing， the scores of vitality，mental health，physical health，social function，somatic role in the study group were higher than those in the control group(P＜0.05)，and the scores of SDS and SAS were lower(P＜0.05). Conclusion：The intervention of Chinese medicine emotional nursing for patients undergoing operation for rectal cancer can relieve their anxiety and depression，and improve their quality of life and nursing satisfaction.