Abstract：Objective：To discuss the effect of Jinkui Wenjing tang on levels of sex hormones and clinical syndrome score in patients with autoimmune premature ovarian failure of kidney deficiency and blood stasis type. Methods： A total of 124 cases of patients with autoimmune premature ovarian failure of kidney deficiency and blood stasis type were enrolled as the study objects， and were divided into the control group and the study group according to the random number table method， 62 cases in each group. The control group was given estradiol cyproterone tablets， and the study group was additionally given the oral administration of Jinkui Wenjing tang based on the treatment of the control group. Both groups were continuously treated for three months. Chemiluminescent method was used to detect levels of follicle-stimulating hormone (FSH)， estradiol(E2)， luteinizing hormone(LH)， and anti- Mullerian hormone(AMH). The examination results of the liver function，the kidney function，stool routine，urine routine，and blood routine were recorded. The clinical syndrome score was evaluated according to standard of Chinese medicine symptom scores. During treatment，menstrual cycle，menstrual volume，and the curative effect were recorded. Results：Before treatment，when compared levels of AMH，E2，LH，and FSH between the two groups，there was no significance being found in the difference(P＞0.05). After treatment，levels of FSH in the two groups were decreased，and the level in the study group was lower than that in the control group；levels of E2 in the two groups were increased，and the level in the study group was higher than that in the control group；the difference was significant(P＜0.05). After treatment，the level of LH in the study group was decreased and lower than that in the control group； the level of AMH in the study group was increased and higher than that in the control group； the difference was significant(P＜0.05). In the control group， when compared levels of LH and AMH before treatment with those after treatment， there was no significance being found in the difference(P＞0.05). Before treatment， when compared clinical syndrome score，menstrual cycle，and menstrual volume between the two groups，there was no significance being found in the difference(P＞0.05). After treatment， menstrual cycles in the two groups were decreased， and the cycle in the study group was shorter than that in the control group；menstrual volume in the two groups was increased，and the volume in the study group was larger than that in the control group； the difference was significant(P＜0.05). After treatment， clinical syndrome score in the study group was lower than that before treatment and that in the control group，the difference being significant(P＜0.05). In the control group， when compared clinical syndrome score before treatment with that after treatment，there was no significance being found in the difference(P＞0.05). The total effective rate was 93.55% in the study group， higher than that of 77.42% in the control group， the difference being significant(P＜0.05). No adverse reactions occurred in the two groups. Conclusion： For patients with autoimmune premature ovarian failure of kidney deficiency and blood stasis type， Jinkui Wenjing tang can significantly improve their levels of sex hormones， reduce clinical syndrome score，and enhance curative effect.