中医外治法治疗不完全性肠梗阻Meta 分析
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R574.2;R244

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Meta- Analysis of External Treatment of Chinese Medicine for Incomplete Intestinal Obstruction
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    摘要:

    目的:系统分析中医外治法治疗不完全性肠梗阻的疗效和安全性。方法:通过检索PubMed、CochraneLibrary、Medline、CNKI、VIP、WANFANG 等数据库,收集2015 年10 月—2020 年10 月期间中医外治法治疗不完全性肠梗阻的随机对照试验文献,采用改良Jadad 量表客观评价纳入的随机对照试验(RCT) 的质量,并用RevMan5.3 软件对结局指标进行Meta 分析。结果:纳入8 篇研究文献,共707 例患者。Meta 分析结果显示,相较于对照组,中医外治法可以提高不完全性肠梗阻的总有效率、治愈率,差异均有统计学意义(P<0.05);但未能改善腹平片、降低手术转换率(P>0.05)。结论:相较于常规药物治疗,中医外治法治疗不完全性肠梗阻疗效更好,但本研究纳入的部分原始文献质量较低,论证强度有限,有效性尚不能得出肯定结论,将来还需要开展多中心、样本量大、方法科学和规范操作的高质量临床研究进一步验证。

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    Abstract:Objective:To systematically analyze the curative effect and safety of external treatment of Chinese medicine for incomplete intestinal obstruction. Methods: By searching for the databases including PubMed, Cochranelibrary, Medline, CNKI, VIP and WANFANG, the randomized controlled trials on external treatment of Chinese medicine for incomplete intestinal obstruction from October 2015 to October 2020 were collected, modified Jadad Scale was used to objectively evaluate the quality of the included RCTs, and RevMan5.3 software was used for Meta- analysis of outcome indexes. Results:Eight literature studies involving 707 cases of patients were included. Meta- analysis results showed that when compared with that in the control group,external treatment of Chinese medicine for incomplete intestinal obstruction could improve the total effective rate and cure rate, differences being significant(P<0.05); but it could not improve the abdominal plain film or reduce the surgical conversion rate(P>0.05). Conclusion:Compared with routine medical treatment, the external treatment of Chinese medicine for incomplete intestinal obstruction is more effective. However,due to the low quality of some source documents involved in this study, and the limitation of argumentation intensity, the effectiveness cannot be affirmed. It should be further verified in the future by carrying out the clinical studies of high quality with multicenter,great sample size,scientific methods,and standardized operation.

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林益群,刘嘉彬,李金峰.中医外治法治疗不完全性肠梗阻Meta 分析[J].新中医,2021,53(13):10-14

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  • 在线发布日期: 2021-07-11
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