Abstract： This paper introduces the experience of professor SHAO Jing in syndrome differentiation and treatment of chest impediment and heart pain from perspective of qi， blood， fluid， and humor. SHAO Jing holds that the key pathogenesis lies in the heart vessel obstruction and the heart losing nourishment. The basic pathogenesis should be divided into two types， namely deficiency and excess； deficiency is mostly manifested by qi deficiency， and excess is mainly manifested by qi stagnation，phlegm turbidity，and blood stasis. As for prescription based on syndrome differentiation，on the one hand，we should distinguish the pathogenesis of abnormal qi，blood，fluid，and humor before prescription；on the other hand，we should give full consideration to the complexity of pathogenesis，take flexible treatment after weighing the primary and secondary aspects of the disease，and when any possible changes of the disease occur.