铁皮石斛粉对2 型糖尿病患者胰岛功能改善的临床研究
DOI:
作者:
作者单位:

作者简介:

通讯作者:

中图分类号:

R587.1

基金项目:

嵊州市科技项目([2018]11-005)


Clinical Study on Dendrobium Candidum Powder in Improving Islet Function of Patients with Type 2 Diabetes Mellites
Author:
Affiliation:

Fund Project:

  • 摘要
  • |
  • 图/表
  • |
  • 访问统计
  • |
  • 参考文献
  • |
  • 相似文献
  • |
  • 引证文献
  • |
  • 资源附件
  • |
  • 文章评论
    摘要:

    目的:探讨铁皮石斛粉对2 型糖尿病(T2DM) 患者胰岛功能的改善情况。方法:纳入110 例T2DM 患者为研究对象,随机分为观察组和对照组,每组55 例,观察组给予铁皮石斛粉治疗,对照组给予安慰剂治疗,治疗2 个月后比较2 组临床疗效。结果:治疗后,观察组临床总有效率为89.09%,高于对照组的3.64%,2 组比较,差异有统计学意义(P<0.05)。治疗前,2 组中医证候积分比较,差异无统计学意义(P>0.05);观察组中医证候积分显著低于治疗前及对照组(P<0.05),而对照 组治疗前后中医证候积分比较,差异无统计学意义(P>0.05)。治疗前,2 组空腹血糖(FBG)、餐后2 h 血糖(P2hBG) 及糖化血红蛋白(HbA1c) 水平相当(P>0.05)。治疗后,观察组FBG、P2hBG 及HbA1c 水平较治疗前及对照组治疗后显著降低(P<0.05),而对照组治疗前后FBG、P2hBG 及HbA1c 水平比较,差异无统计学意义(P>0.05)。2 组治疗前胰岛功能指标空腹胰岛素(FINS)、2 h 胰岛素(2hINS)、胰岛素抵抗指数(Homa-IR) 和胰岛素细胞功能指数(Homa-β) 水平比较,差异无统计学意义(P>0.05);治疗后,观察组FINS、2hINS、Homa-β 水平较治疗前及对照组显著上升,Homa-IR 水平较治疗前及对照组显著降低(P>0.05)。对照组治疗前后FINS、2hINS、Homa-IR、Homa-β 水平比较,差异无统计学意义(P>0.05)。结论:针对T2DM 患者以铁皮石斛粉治疗,效果满意,可有效缓解临床症状、控制血糖及改善胰岛功能。

    Abstract:

    Abstract:Objective:To investigate the effect of Dendrobium candidum powder on the improvement of pancreatic islet function in patients with type 2 diabetes mellites(T2DM). Methods: 110 patients with T2DM were randomly divided into observation group and control group,55 cases in each group. The observation group was treated with Dendrobium candidum powder,and the control group was treated with placebo. After 2 months of treatment,the clinical effects of the two groups were compared. Results:After treatment,the total clinical effective rate of the observation group was 89.09%,which was higher than 3.64% of the control group. The difference between the two groups was statistically significant(P<0.05). Before treatment,there was no significant difference in the scores of TCM syndromes between the two groups(P>0.05); the scores of TCM syndromes in the observation group were significantly lower than those before treatment and the control group(P<0.05),while the scores of TCM syndromes in the control group before and after treatment there was no significant difference(P>0.05). Before treatment, the fasting blood glucose(FBG), postprandial 2 h blood glucose(P2hBG) and glycosylated hemoglobin(HbA1c) levels of the two groups were similar(P>0.05). After treatment,the levels of FBG,P2hBG and HbA1c in the observation group were significantly lower than those before and after treatment in the control group(P< 0.05), while the levels of FBG, P2hBG and HbA1c in the control group were not different before and after treatment(P> 0.05). Before treatment,the pancreatic islet function indexes fasting insulin(FINS) and 2 h insulin(2hINS),insulin resistance index(Homa-IR) and insulin cell function index(Homa-β) levels before treatment in the two groups,there was no significant difference(P>0.05). After treatment,the levels of FINS,2hINS,and Homa- β in the observation group were significantly higher than those before treatment and the control group, and the levels of Homa- IR were significantly lower than those before treatment and the control group(P<0.05). There was no significant difference in the levels of FINS,2hINS,Homa-IR and Homa-β in the control group before and after treatment(P>0.05). Conclusion: Treatment of T2DM patients with Dendrobium candidum powder has satisfactory results. It can effectively relieve clinical symptoms,control blood sugar and improve islet function.

    参考文献
    相似文献
    引证文献
引用本文

王璟,董志春,楼丽颖,罗志芳,蔡国英.铁皮石斛粉对2 型糖尿病患者胰岛功能改善的临床研究[J].新中医,2021,53(12):90-93

复制
分享
文章指标
  • 点击次数:
  • 下载次数:
  • HTML阅读次数:
  • 引用次数:
历史
  • 收稿日期:
  • 最后修改日期:
  • 录用日期:
  • 在线发布日期: 2021-06-23
  • 出版日期: