Abstract： Objective： To observe the clinical effect of Xiaoyukang capsules combined with atorvastatin for chronic subdural hematoma in the senile. Methods： A total of 65 cases of senile patients with chronic subdural hematoma were divided into the control group and the treatment group according to the random number table method，32 and 33 cases in each group respectively. The control group was treated with atorvastatin，and the treatment group was additionally treated with Xiaoyukang capsules based on the treatment of the control group. Both groups were treated for 12 weeks. The changes in hematoma volume and scores of Activities of Daily Living(ADL) and Barthel indexes before and after treatment and the clinical effect in the two groups were observed and compared. Results：The total effective rate was 90.91% in the treatment group and 71.88% in the control group，the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparison of hematoma volume between the two groups(P＞0.05)； after treatment， the hematoma volume in the two groups was decreased when compared with that before treatment(P＜0.05)，and the one in the treatment group was significantly less than that in the control group(P＜0.05). Before treatment， there was no significant difference being found in the comparison of the scores of ADL and Barthel indexes between the two groups(P＞0.05)；after treatment，the ADL score decreased and Barthel index score increased in both groups(P＜0.05)；The improvement of two indexes in the treatment group was more significant than that in the control group(P＜0.05). Conclusion：Xiaoyukang capsule combined with atorvastatin for chronic subdural hematoma in senile patients can improve their clinical effect， promote hematoma absorption，and effectively improve the activities of daily living.