An Analysis of Distribution of Chinese Medicine Syndrome Types and Administration Rules of Brain Dysfunction After Cardiopulmonary Resuscitation Based on Literature
Abstract: Objective: To summarize the distribution of Chinese medicine syndrome types and administration rules of brain dysfunction after cardiopulmonary resuscitation(CPR) by analyzing relevant literature. Methods: Keywords including “brain dysfunction after CPR”,“brain dysfunction after resuscitation”,“brain damage after resuscitation”,“brain dysfunction”,“brain damage”,“brain resuscitation after cardiac arrest”,“Chinese medicine”,“Chinese herbs”,“Chinese herbal treatment”,“Chinese medicine treatment”,“Chinese medicine syndrome type” or “syndrome”,were retrieved in CNKI, VIP and Wanfang databases. According to the inclusion and exclusion criteria, 24 pieces of literature were finally screened,and the data were sorted into Excel 2007 and analyzed by SPSS19.0 statistical software. Results:The top three Chinese medicine syndrome types were the sudden desertion of yang qi type, qi deficiency and blood stasis type and desertion of both qi and yin type. The top three prescriptions or Chinese patent medicine were Shenfu injection,Shengmai injection and Ligustrazine injection. The top six single Chinese herbs in terms of application frequency were Radix et Rhizoma Ginseng Rubra, Radix Aconiti Lateralis Praeparata, Rhizoma Chuanxiong, Radix Ophiopogonis, Fructus Schisandrae Chinensis and Radix Angelicae Sinensis. Cluster analysis showed four herb combinations: (1) Radix Scutellariae, Radix Isatidis, Concha Margaritiferae Usta, Cornu Bubali, Flos Lonicerae Japonicae; (2) Rhizoma Chuanxiong, Radix Paeoniae Rubra, Flos Carthami, Radix Angelicae Sinensis, Radix et Rhizoma Salviae Miltiorrhizae, Radix Platycodonis, Radix Bupleuri, Fructus Aurantii, Radix et Rhizoma Ginseng, Radix Achyranthis Bidentatae, Radix Rehmanniae; (3) Moschus, Borneolum Syntheticum, Fructus Gardeniae, Radix Curcumae; (4) Calculus Bovis, Rhizoma Coptidis, Cinnabaris, Margarita,Realgar. Conclusion:Deficiency syndrome is the main type of Chinese medicine syndrome types after CPR. Most herbs in application are tonic Chinese patent medicine injection and Chinese herbs,and Chinese medicine of clearing heat and detoxification,promoting blood circulation and removing blood stasis and detoxification and reviving mind also have certain effects.