Abstract：Objective：To observe the clinical effect of Tongyu Xiaoyan tang combined with routine medical measures for chronic prostatitis of type III with dampness-heat stasis syndrome. Methods：A total of 120 cases of patients were randomly divided into the control group and the observation group， 60 cases in each group. Both groups were given the oral administration of tamsulosin hydrochloride sustained release capsules and Qianlie Beixi capsules，as well as comprehensive nursing measures including psychological nursing， dietary guidance and lifestyle intervention； the observation group was additionally given sitz bath with Tongyu Xiaoyan tang．Both groups were treated for six weeks. Before treatment and after sixweek treatment， the scores of National Instituted of Health- Chronic Prostatitis Symptom Index(NIH- CPSI) and Chinese medicine symptoms in the two groups were assessed ； the levels of zinc ions(Zn2+) and prostate specific antigen(PSA) in prostatic fluid were examined． The curative effect of disease and Chinese medicine syndromes in the two groups were compared．Results：After treatment，the scores of pain and discomfort，voiding symptoms and quality of life in NIH-CPSI and the total scores in the two groups were decreased when compared with those before treatment(P＜0.01)； the above three scores and the total score in the observation group were lower than those in the control group(P＜0.01)．The curative effect of disease and Chinese medicine syndromes in the observation group was better than that in the control group， differences being significant(P＜0.05)．The levels of Zn2 + and PSA in prostatic fluid in the two groups were increased when compared with those before treatment(P＜0.01)，and the levels in the observation group were higher than those in the control group(P＜0.01)．Conclusion：Based on routine medical measures，the additional application of sitz bath with Tongyu Xiaoyan tang for patients with chronic prostatitis with dampness- heat stasis syndrome can improve the prostate function， clinical symptoms，and their quality of life.