Objective： To observe the curative effect of rehabilitation therapy based on risk assessment on the heart rehabilitation combined with meridian exercise of Chinese medicine on patients after stent implantation of coronary artery. Methods：A total of 98 cases of patients undergoing stent implantation of coronary artery were divided into the control group and the observation group according to the random number table method，49 cases in each group. After surgery，the control group was given the combined therapy of routine nursing and rehabilitation therapy based on risk assessment on the heart rehabilitation，and the observation group was additionally given the intervention of meridian exercise based on the treatment of the control group. The scores of Hamilton Anxiety Scale(HAMA)，Hamilton Depression Scale(HAMD)，clinical symptoms， and quality of life were compared between the two groups before and after intervention. Results： After intervention， the scores of HAMA and HAMD in the two groups were decreased when compared with those before intervention(P＜0.05)，and the two scores in the observation group were lower than those in the control group(P＜0.05). After intervention，the scores of clinical symptoms including poor appetite， lack of strength， abdominal distension， and abnormal bowel sound in the two groups were decreased when compared with those before intervention(P＜0.05)， and each score in the observation group was lower than that in the control group(P＜0.05). After intervention， the scores of quality of life including psychological state，physiological state，environmental domain，and social relation in the two groups were increased when compared with those before intervention(P＜0.05)， and each score in the observation group was higher than that in the control group(P＜ 0.05). Conclusion： In the intervention of patients after stent implantation of coronary artery， the combined treatment of rehabilitation therapy based on risk assessment on the heart rehabilitation and meridian exercise conduces to postoperative recovery，improving symptoms and quality of life，and relieving anxiety and depression.