Abstract：Objective：To observe the clinical effect of moxa- box moxibustion combined with press- needle for lumbar muscle strain. Methods： A total of 60 cases of patients with lumbar muscle strain were randomly divided into the control group and the observation group，30 cases in each group. The control group was treated with celecoxib capsules，and the observation group was treated with moxa-box moxibustion combined with press-needle. Both groups were treated for 20 days. The clinical effect，Visual Analogue Scale(VAS) scores and Chinese version of the Oswestry Disability Index(CODI) in the two groups were observed and compared. Results： After treatment， the total effective rate was 93.33% in the observation group and 73.33% in the control group，the difference being significant(P＜0.05). Before treatment，there was no significant difference being found in the comparison of VAS scores between the two groups(P＞0.05). After treatment， VAS scores in the two groups were decreased when compared with those before treatment(P＜0.05)，and the score in the observation group was lower than that in the control group(P＜0.05). Before treatment， there was no significant difference being found in the comparison of scores of pain，single function and comprehensive functions between the two groups(P＞0.05)；after treatment，the above indexes in the two groups were decreased when compared with those before treatment(P＜0.05)， and the indexes in the observation group were lower than those in the control group(P＜0.05). after treatment， the CODI of the observation group was lower than that of the control group， the difference was statistically significant(P＜0.05). Conclusion：Moxa-box moxibustion combined with press-needle for lumbar muscle strain can improve clinical effect，effectively relieve pain，decrease lumbar dysfunction，whose effect is better than that of celecoxib capsules.