Abstract：Objective：To observe the clinical study on regulating measures based on emollient and anti-pruritus thought in Chinese medicine for atopic dermatitis(AD). Methods：A total of 96 cases of AD patients with blood deficiency and winddryness syndrome were randomly divided into the observation group and the control group，48 cases in each group. Both groups were given mometasone furoate cream for skin lesions， oral loratadine tablets， and comprehensive nursing measures for living environment guidance， bathing guidance， moisturizer， emollient use and diet guidance. Under the thinking of moisturizing and relieving itching，the observation group was given TCM diet care，Runfu Zhiyang prescription external washing and comfrey baby ointment. Both groups were treated for three months. Before and after three months treatment， the scores of SCORing Atopic Dermatitis(SCORAD) and blood deficiency and wind- dryness syndrome were measured. After treatment，nursing satisfaction was evaluated. Results：After treatment，the scores of A，B and C as well as the total scores of SCORAD in the two groups were decreased when compared with those before treatment(P＜ 0.01)，and the above scores in the observation group were lower than those in the control group(P＜0.01)；the score of blood deficiency and wind-dryness syndrome in the observation group was lower than that in the control group(P＜0.01)； the nursing satisfaction in the observation group was higher than that in the control group(P＜0.05). Conclusion：Based on routine western medicine treatment and nursing， the regulating measures including Chinese medicine diet nursing， external washing with Runfu Zhiyang prescription，and Zicao baby ointment under the emollient and anti-pruritus thought in Chinese medicine can further alleviate the skin lesions of AD，decrease the score of blood deficiency and wind-dryness syndrome，and improve nursing satisfaction.