基于聚类分析总结姜劲挺治疗腰痛用药规律研究
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R255.9

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国家自然科学基金项目(81660799);国家中医药管理局第四批全国中医(临床、基础)优秀人才研修项目(国中医药人教发[2017]24号)


Study and Summary of JIANG Jingting's Administration Rules in Treating Low Back Pain Based on Cluster Analysis
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    摘要:

    目的:通过统计学方法分析姜劲挺教授治疗腰痛的用药规律。方法:收集2017 年3 月—2019 年3 月姜劲挺教授治疗腰痛的门诊和住院病例,从病例中选择符合纳入标准的处方196 首,运用EXCEL2020 对处方中的药物进行数据录入并采用二 元分类变量法二元化赋值,用SPSS26.0 软件对高频药物进行聚类分析。结果:196 首处方中应用中药147 味,共计4 172 频次,每首处方药味数在16~26 味之间,平均味数是21.29;使用频次>30 次为34 味。聚类分析可将34 味高频药分为7 类,涉及的药物种类有补益药、祛风湿痰瘀药、活血行气止痛药、疏肝安神药等;涉及方剂有黄芪桂枝五物汤、当归黄芪汤、瓜蒌薤白半夏汤、仙鹤决明汤、独活寄生汤等。结论:姜劲挺教授治疗腰痛以扶正驱邪、益气通络为原则;重肝脾肾,善调情志;同时颈胸腰同治。

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    Abstract: Objective: To analyze the administration rules of professor JIANG Jingting in treating low back pain with statistical method. Methods:The outpatient and inpatient cases of Professor JIANG treating low back pain from March 2017 to March 2019 were collected,and 196 prescriptions that met the inclusion criteria were selected from these cases. Chinese medicine used in the prescriptions was recorded by EXCEL2020; binary classification method was conducted for bivariate data assignment; cluster analysis of Chinese medicine with a high frequency was performed with SPSS26.0 software. Results:There were 147 Chinese medicines used in 196 prescriptions,with a total of 4,172 times,and the number of Chinese medicines per prescription ranged from 16 to 26, with the average number being 21.29; there were 34 Chinese medicines with a frequency of use more than 30 times. According to cluster analysis, 34 Chinese medicines with a high frequency could be classified into seven categories,involving tonifying medicine,medicine for dispelling wind,dampness, phlegm and stasis, medicine for activating blood, moving qi and alleviating pain, medicine for smoothing the liver and calming the mind, and so on; prescriptions that were involved with these 34 Chinese medicines included Huangqi Guizhi Wuwu tang, Danggui Huangqi tang, Gualou Xiebai Banxia tang, Xianhe Jueming tang, Duhuo Jisheng tang, and so on. Conclusion:Professor JIANG Jingting treats low back pain with the principles of reinforcing the healthy qi and eliminating the pathogenic factors, as well as tonifying qi and freeing the collateral vessels. He focuses on the liver, the spleen and the kidney,and is expert in regulating patients' emotions. The neck,chest and low back are treated simultaneously.

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张博,姜炫合,郑吉元,马宏武,窦中信,徐欣,王强强,指导:姜劲挺.基于聚类分析总结姜劲挺治疗腰痛用药规律研究[J].新中医,2021,53(8):201-205

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  • 在线发布日期: 2021-04-29
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