Abstract： Objective： To observe the effect of Chinese medicine emotional nursing and Yangxin tang combined with routine medical measures on patients with schizophrenia. Methods：A total of 72 cases of patients of dual deficiency of the heart-spleen type were included in the study and were divided into the observation group and the control group according to the random number table method，36 cases in each group. Both groups were treated with routine antipsychotic drugs and nursing，and the observation group was additionally treated with Chinese medicine emotional nursing and Yangxin tang. Both groups were treated for four weeks. Before treatment and after four- week treatment，the differences of family cohesion， sleep quality and coping styles between the two groups were compared. Results：After treatment，the scores of genuine intimacy and ideal intimacy in the observation group were increased when compared with those before treatment，and the score of intimacy dissatisfaction was lower than that before treatment， differences being significant(P＜0.01，P＜0.05). In the control group，there was no significant difference being found in the comparison of the above three scores before and after treatment(P＞0.05). The scores of genuine intimacy and ideal intimacy in the observation group were higher than those in the control group，and the score of intimacy dissatisfaction was lower，differences being significant(P＜0.05). The scores and total scores of seven indexes in Pittsburgh Sleep Quality Index Scale(PSQI) in the two groups were decreased when compared with those before treatment(P＜0.05)，and the above scores in the observation group were lower than those in the control group(P＜0.05). The scores of positive coping styles in the two groups were higher than those before treatment， and the scores of negative coping styles were lower，differences being significant(P＜0.01). The score of positive coping style in the observation group was higher than that in the control group，and the score of negative coping style was lower，differences being significant(P＜0.01). Conclusion： Based on the routine medical measures， the additional application of Chinese medicine emotional nursing combined with Yangxin tang for patients with schizophrenia of dual deficiency of the heart-spleen type can enhance the clinical effect by improving their family cohesion and sleep quality as well as promoting their positive coping styles.