Abstract：Objective：To observe the effect of individualized Chinese medicine nursing combined with emotional nursing on adverse conditions and quality of life of patients with Parkinson disease. Methods： A total of 90 cases of patients with Parkinson disease were divided into the control group and the observation group according to the random number table method，45 cases in each group. The control group was given routine nursing，and the observation group was additionally given individualized Chinese medicine nursing combined with emotional nursing based on the nursing of the control group. The quality of life，the degree of anxiety and depression，and activities of daily living before and after intervention were compared between the two groups. Results：Before intervention，there was no significant difference being found in the comparison of each score of quality of life between the two groups(P＞0.05). After intervention， each score of quality of life in the two groups was increased when compared with that before intervention，and each score in the observation group was higher than that in the control group， differences being significant(P＜0.05). Before intervention， there was no significant difference being found in the comparison of scores of Hamilton Anxiety Scale(HAMA) and Hamilton Depression Scale(HAMD) between the two groups(P＞0.05). After intervention，HAMA and HAMD scores in the two groups were decreased when compared with those before intervention， and the scores in the observation group were lower than those in the control group， differences being significant(P＜0.05). Before intervention，there was no significant difference being found in the comparison of scores of activities of daily living between the two groups(P＞0.05). After intervention，scores of activities of daily living in the two groups were increased when compared with those before intervention，and the score in the observation group was higher than that in the control group， differences being significant(P＜0.05). Conclusion： For patients with Parkinson disease，the intervention of individualized Chinese medicine nursing combined with emotional nursing can significantly relieve adverse emotions，and enhance activities of daily living and quality of life.