Abstract： Objective： To discuss the effect of abdominal massage on constipation and related symptoms in patients undergoing cancer chemotherapy. Methods：A total of 80 cases of patients undergoing cancer chemotherapy were selected as the study objects and divided into the control group and the study group according to the random number table method， 40 cases in each group. The control group was given routine nursing，and the study group was additionally given abdominal massage based on the treatment of the control group. The nursing effect in the two groups were compared. Results：Before intervention，the Wexner scores were 25.69±3.52 and 25.32±3.02 points in the two groups respectively，there being no significance in the difference(t=0.126，P=0.865＞0.05). After intervention，the Wexner score was 18.65±5.21 points in the control group and 10.52±2.36 points in the study group. After repeated analysis of variance，the Wexner scores in the two groups were decreased when compared with those before intervention，and the score in the study group was lower than that in the control group，the difference being significant(t=8.698，P=0.000＜0.05). After intervention，the scores of defecation difficulties，defecation time and defecation frequency in the two groups were decreased when compared with those before intervention， and the above scores in the study group were lower than those in the control group(P＜0.05). Conclusion： Abdominal massage can effectively improve constipation and related symptoms in patients undergoing cancer chemotherapy，which is simple，economical，noninvasive and easy to be accepted by patients.