益肾利湿排毒汤联合前列地尔治疗慢性肾功能衰竭临床研究
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R692.5

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Clinical Study on Yishen Lishi Paidu Tang Combined with Alprostanil for Chronic Renal Failure
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    摘要:

    目的:观察益肾利湿排毒汤联合前列地尔治疗慢性肾功能衰竭的临床疗效。方法:选取84 例慢性肾功能衰竭患者,随机分为研究组与对照组,每组42 例。2 组均给予对症治疗,对照组给予前列地尔治疗,研究组在对照组基础上给予益肾利湿排毒汤治疗。2 组均治疗2 周。比较2 组治疗前后中医证候积分、肾功能指标及血脂指标,比较2 组临床疗效。结果:治疗后,研究组中医证候积分低于对照组(P<0.05)。治疗后,2 组24 h 尿蛋白定量比较,差异无统计学意义(P>0.05);研究组血肌酐(SCr)、血尿素氮(BUN)、甘油三酯(TG) 及总胆固醇(TC) 水平均低于对照组(P<0.05),24 h 尿量大于对照组(P<0.05)。研究组总有效率为88.1%,高于对照组的61.9%(P<0.05)。结论:益肾利湿排毒汤联合前列地尔治疗慢性肾功能衰竭,能够明显改善患者的临床症状、肾功能及血脂指标。

    Abstract:

    Abstract:Objective:To observe the clinical effect of the therapy of Yishen Lishi Paidu tang combined with alprostanil on chronic renal failure. Methods:A total of 84 patients with chronic renal failure were selected and randomly divided into the study group and the control group, 42 cases in each group. Both groups were given symptomatic treatment; the control group was treated with alprostadil,and the study group was additionally given Yishen Lishi Paidu tang based on the treatment of the control group. Both groups were treated for two weeks. The Chinese medicine syndrome scores,indexes related to kidney function and blood lipid were compared between the two groups before and after treatment,and the clinical effect in the two groups was compared. Results: After treatment,the Chinese medicine syndrome scores in the study group were lower than those in the control group(P<0.05). After treatment,there was no significant difference in the comparison of 24 h urinary protein between the two groups(P>0.05); the levels of serum creatinine(SCR), blood urea nitrogen(BUN), triglyceride(TG) and total cholesterol(TC) in the study group were lower than those in the control group(P<0.05),and the 24 h urine volume was larger than that in the control group(P<0.05). The total effective rate was 88.1% in the study group,higher than that of 61.9% in the control group(P<0.05). Conclusion: The therapy of Yishen Lishi Paidu tang combined with alprostanil can significantly improve the clinical symptoms, kidney function and blood lipid indexes of patients with chronic renal failure.

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梁亚林,王长安,杨青彦,李冰玉,袁胜平.益肾利湿排毒汤联合前列地尔治疗慢性肾功能衰竭临床研究[J].新中医,2021,53(8):78-81

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  • 在线发布日期: 2021-04-29
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