Abstract： Objective： To analyze the characteristics of the use of shu points in the treatment of acupuncture and moxibustion for shoulder and hand syndrome after stroke and summarize the rules of their application. Methods：Literatures related to the treatment of post-stroke shoulder and hand syndrome by acupuncture and moxibustion published from January 2008 to June 2019，were retrieved from Medline，Pubmed，Embase，CNKI，VIP and Wanfang databases. Key information such as point name related to “shu” was extracted from literatures meeting the criteria，and data mining was carried out by using clustering algorithm and Apriori algorithm. Results：A total of 244 literatures were included，involving 143 points and 2 257 times of shu points. The selected shu points were all over the fourteen main meridians and all specific points，but they had an obvious central tendency. The top five shu points in terms of frequency of use were jianyu(LI15)，quchi(LI11)，hegu (LI4)，jianliao(SJ14) and waiguan(SJ5)，accounting for 36.02% of the total frequency. The selected points were mainly on the large intestine meridian， the triple energizer meridian， the small intestine meridian and the upper limb， and attached importance to the use of specific points where meridian qi meets together，connects with each other and disperses，such as yang meridian shu points，extra point and five shu points，confluence points，yuan-source point and confluence points of the eight extraordinary collaterals. Clustering analysis of high-frequency point selection was carried out and grouped into five types；15 association rules were obtained through association rule analysis. Conclusion：The treatment of acupuncture and moxibustion to treat shoulder and hand syndrome after stroke， should take regulating and normalizing qi and blood， unblocking the collaterals and eliminating impediment as its principle，and combine factors such as phlegm，deficiency and stasis to carry out syndrome differentiation and treatment. The rules of point selection revealed by clustering and association analysis of high-frequency points can provide theoretical basis and reference for clinical application such as ensuring curative effect and rational point selection.