Abstract： Objective： To observe the clinical effect of Shenbi tang combined with sodium hyaluronate for alcoholic femoral head necrosis. Methods： A total of 56 cases of patients with alcoholic femoral head necrosis were selected and divided into the study group and the control group according to the random number table method，28 cases in each group. The control group was treated with sodium hyaluronate，and the study group was additionally treated with Shenbi tang based on the treatment of the control group. The clinical effect in the two groups was compared. Before and after treatment，the hip joint function scores， the blood lipid indexes including total cholesterol(TC)， triglyceride(TG)， low- density lipoprotein cholesterol(LDL- C) and high- density lipoprotein cholesterol(HDL- C) as well as the hemorheology indexes including blood plasma viscosity，red blood cell hematocrit，whole blood high shear viscosity and whole blood low shear viscosity in the two groups were detected. Results：The excellent and good rate was 92.86% in the study group，higher than that of 71.43% in the control group， the difference being significant(P＜0.05). Before treatment， there was no significant difference being found in the comparison of the scores of the pain， walking distance， range of motion of joint and activities of daily living between the two groups(P＞0.05). After treatment，the scores of the pain，walking distance，range of motion of joint and activities of daily living in the two groups were increased when compared with those before treatment，and the above scores in the study group were all higher than those in the control group，differences being significant(P＜0.05). Before treatment， there were no significant difference being found in the comparison of whole blood low shear viscosity， plasma viscosity， whole blood high shear viscosity and red blood cell hematocrit between the two groups(P＞0.05). After treatment， whole blood low shear viscosity，plasma viscosity，whole blood high shear viscosity and red blood cell hematocrit in the two groups were decreased when compared with those before treatment，and the above indexes in the study group were lower than those in the control group， differences being significant(P＜0.05). Before treatment， there were no significant difference being found in the comparison of the levels of HDL- C， LDL- C， TC and TG between the two groups(P＞0.05). After treatment，HDL-C levels in the two groups were increased when compared with those before treatment，and the levels of LDL-C，TC and TG were decreased；the level of HDL-C in the study group was higher than that in the control group，and the levels of LDL-C，TC and TG were lower，differences being significant(P＜0.05). Conclusion：Shenbi tang combined with sodium hyaluronate for patients with alcoholic femoral head necrosis can improve their levels of hemorheology and blood lipid，and enhance the curative effect.