Abstract：Objective：To observe the effect of Zishen Yitai granules combined with western medicine on level of antimullerian hormone(AMH) and pregnancy in patients with habitual abortion. Methods： A total of 88 cases of patients with habitual abortion of spleen-kidney deficiency type were divided into the observation group and the control group according to the random number table method，44 cases in each group. Both groups were given the injection of chorionic gonadotrophin and progesterone injection， and the observation group was additionally given Zishen Yitai granules. Both groups were continuously treated for three months until pregnancy， and the treatment was discontinued in menstrual period. Before treatment and after three- month treatment， Chinese medicine syndrome scores were evaluated； the level of AMH was detected； the clinical effect， the incidence of adverse reactions， and the pregnancy were compared between the two groups. Results：After treatment，the total effective rate of clinical effect was 90.91% in the observation group，and 63.64% in the control group，the difference being significant(P＜0.01). In the two groups，Chinese medicine syndrome scores were decreased when compared with those before treatment， differences being significant(P＜0.01)； the scores in the observation group were lower than those in the control group，the difference being significant(P＜0.01). In the two groups， AMH concentration was increased when compared with that before treatment，differences being significant(P＜0.01)；the concentration in the observation group was higher than that in the control group， the difference being significant(P＜0.01). According to information from the follow- up， the success rate of pregnancy was 90.91% in the observation group， and 63.64% in the control group，the difference being significant(P＜0.01). The rate of spontaneous delivery in the observation group was higher than that in the control group(P＜0.05). There was no significant difference being found in the comparison of the incidence of adverse reactions in perinatal period between the two groups(P＞0.05). Conclusion：The therapy of Zishen Yitai granules combined with western medicine has significant clinical effect in the treatment of patients with habitual abortion of spleen-kidney deficiency type，which can effectively improve their clinical symptoms，regulate AMH concentration，and improve pregnancy rate.