Abstract： Objective： To observe the clinical effect of Chinese medicine nursing measures and oral administration of Hanchuan Zupa granules based on routine medical measures intervening bronchial asthma in acute exacerbation. Methods：A total of 100 cases of patients with bronchinal asthma in acute exacerbation of external cold and phlegm- fluid retention syndrome who meet the requirements were randomly divided into the observation group and the control group，50 cases in each group. The two groups were given inhalation treatment with salbutamol aerosol， and nursing measures including cognitive education，psychological nursing and dietary nursing. The observation group was additionally treated with Hanchuan Zupa granules combined with Chinese medicine nursing measures. Both groups were treated for one week. Before treatment and after one- week treatment， the symptom scores of wheezing， cough， expectoration， thoracic diaphragm distension and discomfort and wheezing sound in the throat were evaluated； forced expiratory volume in one second(FEV1) and peak expiratory flow(PEF) were measured；the percentage of predicted value of FEV1(FEV1%)，the percentage of predicted value of PEF% (PEF% ) and day- night volatility of PEF were calculated. After treatment for one week， nursing satisfaction was evaluated. Results：After treatment，the clinical effect in the observation group was better than that in the control group(P＜ 0.05). The clinical symptom scores and PEF% values in the two groups were decreased when compared with those before treatment，and FEV1% values were increased when compared with those before treatment，differences being significant(P＜ 0.01)； the clinical symptom score and PEF% value in the observation group were lower than those in the control group， FEV1% value was higher， the difference being significant(P＜0.01). The nursing satisfaction in the observation group was higher than that in the control group(P＜0.05). Conclusion： Based on routine medical measures in modern medicine， the additional therapy of Chinese medicine nursing measures and oral administration of Hanchuan Zupa granules for bronchial asthma of external cold and phlegm- fluid retention syndrome in acute exacerbation can better control symptoms of asthma attack，improve the lung function，clinical effect and nursing satisfaction.